{"id":"W2984527456","doi":"10.1182/blood-2019-123709","title":"Targeted Inhibition of the NUP98-NSD1 Fusion Oncogene in AML","year":2019,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Precision Nanosystems (Canada)","funders":"","keywords":"Cancer research; Suramin; Transplantation; Medicine; Chemistry; Molecular biology; Biology; Internal medicine; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001587715,0.0002900364,0.0002432391,0.0002411537,0.0001026844,0.0001905606,0.0002045091,0.0002373457,0.0008476966],"category_scores_gemma":[0.00007314979,0.0000898825,0.0002103918,0.0001336655,0.0001968955,0.0001545929,0.0001739842,0.0004636982,0.0002130612],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003397783,"about_ca_system_score_gemma":0.0001630624,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003077128,"about_ca_topic_score_gemma":0.0005580824,"domain_scores_codex":[0.999902,0.000009905148,0.000009518822,0.00001934717,0.00004182988,0.00001738189],"domain_scores_gemma":[0.999964,0.000007633424,0.00001111417,0.000004352572,0.000004546308,0.000008361638],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001593032,0.00007080629,0.0002149475,0.0000751249,0.000007938625,0.0000368898,0.00001480158,0.0002683658,0.9945697,0.0001569345,0.0001069563,0.0043181],"study_design_scores_gemma":[0.00004161732,0.0006068518,0.001614832,0.000004845417,0.00002489035,0.000263543,0.00001227281,0.001770264,0.9909906,0.00005656804,0.004610415,0.000003244824],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905213,0.00254502,0.004543913,0.0001267592,0.00003485326,0.00008189185,0.0004051558,0.0001383453,0.001602862],"genre_scores_gemma":[0.9942629,0.001284384,0.002894195,0.00003356912,0.000005660793,0.0000548994,0.0003379408,0.00001146882,0.001114879],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008476966,"threshold_uncertainty_score":0.00283581,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01089944598755528,"score_gpt":0.2580916928867049,"score_spread":0.2471922468991496,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}