{"id":"W2984547986","doi":"10.1213/ane.0000000000004481","title":"Tranexamic Acid for Acute Hemorrhage: When Is Enough Evidence Enough?","year":2019,"lang":"en","type":"letter","venue":"Anesthesia & Analgesia","topic":"Trauma, Hemostasis, Coagulopathy, Resuscitation","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; University of Toronto; Hospital for Sick Children","funders":"","keywords":"Tranexamic acid; Medicine; Antifibrinolytic; Intensive care medicine; Randomized controlled trial; Evidence-based medicine; Clinical trial; Dosing; Population; Fibrinolysis; Anesthesia; Surgery; Alternative medicine; Internal medicine; Blood loss","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02947344,0.0011742,0.006690892,0.005100932,0.00167414,0.006334337,0.00471315,0.00887687,0.01487676],"category_scores_gemma":[0.1614986,0.001191132,0.002680523,0.004985639,0.002921763,0.01108888,0.002343399,0.009655486,0.004591932],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003357928,"about_ca_system_score_gemma":0.005786278,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003801944,"about_ca_topic_score_gemma":0.008807183,"domain_scores_codex":[0.9800043,0.007084778,0.007733364,0.0009430932,0.003907652,0.0003267493],"domain_scores_gemma":[0.8398367,0.1252361,0.01516706,0.002533371,0.01379147,0.003435448],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0009472743,0.00005657639,0.0007759412,0.120954,0.001891122,0.0003171199,0.0003365534,0.0002737506,0.0005329364,0.009585927,0.5278472,0.3364817],"study_design_scores_gemma":[0.0006993606,0.0002283921,0.002042078,0.3379608,0.00284704,0.0005195695,0.0005392324,0.000624755,0.0002954431,0.02095861,0.6331374,0.0001473394],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"commentary","genre_scores_codex":[0.0008153141,0.6488423,0.001716237,0.3025956,0.03366156,0.0004768372,0.001851328,0.00009081506,0.009949937],"genre_scores_gemma":[0.01502674,0.6671541,0.01455607,0.2578588,0.03677651,0.001524863,0.0018183,0.0001897386,0.005094829],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.02947344,"threshold_uncertainty_score":0.1558723,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04318172232940162,"score_gpt":0.3086274684186694,"score_spread":0.2654457460892679,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}