{"id":"W2985003976","doi":"","title":"Nonclinical safety of SAR422459 following subretinal injection in both eyes of monkeys","year":2017,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Retinal and Optic Conditions","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canadian Nuclear Laboratories","funders":"","keywords":"Ophthalmology; Medicine; Optometry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.001101749,0.0001334689,0.0004634527,0.0002139418,0.0003127615,0.00001467748,0.0003633329,0.0001073364,0.00008337879],"category_scores_gemma":[0.003468356,0.0001131417,0.0001271246,0.0004168612,0.005338458,0.0002920911,0.0001995406,0.000276719,0.000007642786],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007057754,"about_ca_system_score_gemma":0.0005743508,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006544014,"about_ca_topic_score_gemma":0.000015688,"domain_scores_codex":[0.9982507,0.00009965945,0.0005550158,0.0003922192,0.0004064468,0.0002959979],"domain_scores_gemma":[0.9985949,0.000267952,0.0004214369,0.0003439612,0.0001868246,0.0001848947],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001104238,0.000146836,0.6533142,0.00002086209,0.00001307686,0.0001229448,0.0003579124,0.000006153214,0.3452878,0.0003808788,0.000003150297,0.0002358461],"study_design_scores_gemma":[0.0006762511,0.001432232,0.8815032,0.0002702191,0.0000319959,0.0001863852,0.000258016,0.0003405381,0.1117672,0.00344236,0.000003382907,0.00008825366],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909347,0.00002169342,0.000007536398,0.000603651,0.000229081,0.0002351019,0.000005301548,0.00000811216,0.007954819],"genre_scores_gemma":[0.9980661,0.000003567906,0.001676427,0.00004266106,0.00004180531,0.0000101016,0.000002938272,0.000006428361,0.0001499763],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2335206,"threshold_uncertainty_score":0.9973685,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05929468107968498,"score_gpt":0.408212799972101,"score_spread":0.348918118892416,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}