{"id":"W2985177726","doi":"10.25251/skin.3.supp.12","title":"An oral, selective tyrosine kinase 2 inhibitor, BMS-986165, improves quality of life in psoriasis: results from a Phase 2 study","year":2019,"lang":"en","type":"article","venue":"SKIN The Journal of Cutaneous Medicine","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University; Probity Medical Research","funders":"","keywords":"Psoriasis; Tyrosine-kinase inhibitor; Medicine; Phase (matter); Pharmacology; Quality of life (healthcare); Chemistry; Internal medicine; Dermatology; Cancer; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008657599,0.0009070704,0.001550366,0.0002836878,0.0002463608,0.0005374964,0.0004526167,0.0006669791,0.003469785],"category_scores_gemma":[0.0004206345,0.0002697773,0.0009762369,0.000378454,0.0004377718,0.0004895605,0.0001691718,0.002092708,0.0005816521],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003201136,"about_ca_system_score_gemma":0.0005174229,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007899838,"about_ca_topic_score_gemma":0.00200068,"domain_scores_codex":[0.9998035,0.00007766549,0.00001129688,0.00002434964,0.00003718269,0.0000460536],"domain_scores_gemma":[0.9997093,0.00008434321,0.00005876011,0.00002381075,0.00002185758,0.0001019395],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.492672,0.05881061,0.005593643,0.002400356,0.003153046,0.0004018682,0.0001453985,0.001803046,0.08263611,0.0002508074,0.006801732,0.3453313],"study_design_scores_gemma":[0.5263647,0.4218032,0.03616256,0.0001294361,0.00190704,0.0005909997,0.00008593441,0.001290502,0.00711074,0.0002868611,0.004227886,0.00004002481],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.981293,0.01266492,0.0005004863,0.0006276212,0.0001383472,0.0007884981,0.0009166464,0.0001206173,0.002949834],"genre_scores_gemma":[0.9836535,0.01025046,0.001051933,0.001042365,0.0002630666,0.0005318603,0.001630535,0.00003178348,0.001544587],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003469785,"threshold_uncertainty_score":0.01160765,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02163757621450731,"score_gpt":0.3057167029094791,"score_spread":0.2840791266949718,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}