{"id":"W2985230452","doi":"10.1093/neuonc/noab196.861","title":"TAMI-79. THERAPEUTIC REVERSAL OF PRENATAL PONTINE ID1 SIGNALING IN DIPG","year":2021,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"","keywords":"Cancer research; Epigenetics; Biology; Mutation; Histone; Transcriptome; GATA2; Gene; Gene expression; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000668017,0.000316829,0.0003327216,0.0002356026,0.0001283913,0.0001611501,0.0003178926,0.0002645807,0.001609311],"category_scores_gemma":[0.00006691812,0.00007122097,0.0002032375,0.0001709179,0.000221055,0.0001247744,0.0001395722,0.0007241071,0.0002925949],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002426096,"about_ca_system_score_gemma":0.0003363332,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007219865,"about_ca_topic_score_gemma":0.001313825,"domain_scores_codex":[0.9999614,0.000003843239,0.000001888985,0.000007185624,0.000008025842,0.00001766028],"domain_scores_gemma":[0.9999764,0.000002491951,0.000004678851,0.000002890074,0.000001780063,0.00001182884],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004907786,0.001480658,0.001070263,0.0005636912,0.00008666953,0.001597572,0.00008700626,0.0009005041,0.8904622,0.001443386,0.002505776,0.09489448],"study_design_scores_gemma":[0.002597069,0.02339995,0.01791052,0.00005869141,0.000218597,0.005065984,0.0001537769,0.003570269,0.9052085,0.0007984886,0.04098219,0.00003601412],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882004,0.003915171,0.001973335,0.0003258808,0.0001731259,0.0001852536,0.0007322896,0.0003835908,0.004110958],"genre_scores_gemma":[0.995162,0.001284293,0.0009287829,0.0001426931,0.00001218132,0.00009442313,0.0005860448,0.00002093045,0.001768746],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001609311,"threshold_uncertainty_score":0.00538373,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02319423679850811,"score_gpt":0.30199445227612,"score_spread":0.2788002154776119,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}