{"id":"W2985354612","doi":"10.3390/genes10110932","title":"Cell-Specific DNA Methylation Signatures in Asthma","year":2019,"lang":"en","type":"review","venue":"Genes","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Chicoutimi","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Epigenetics; DNA methylation; Biology; Epigenomics; Methylation; Genetics; Immune system; Phenotype; Genome-wide association study; Immunology; Asthma; Cell type; DNA; Gene; Cell; Genotype; Gene expression; Single-nucleotide polymorphism","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002770596,0.0004617522,0.000768599,0.001342005,0.0001670158,0.0004924012,0.0004786249,0.0006294445,0.002262331],"category_scores_gemma":[0.0004464492,0.000158757,0.0002933759,0.001300393,0.0003476554,0.0005353199,0.0004488972,0.0009162273,0.0009262944],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000448325,"about_ca_system_score_gemma":0.0005966981,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001160171,"about_ca_topic_score_gemma":0.00205863,"domain_scores_codex":[0.9998856,0.00002236685,0.00001639388,0.00002794851,0.00003629577,0.00001135326],"domain_scores_gemma":[0.9998668,0.00006477338,0.0000223436,0.00000412271,0.00003256796,0.000009470623],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007134626,0.00002513452,0.0006097008,0.01500955,0.00009896316,0.000243924,0.00008317662,0.0003619182,0.005105787,0.002699379,0.01914804,0.9565431],"study_design_scores_gemma":[0.00001199869,0.00009056427,0.004738807,0.004119508,0.0001992392,0.003596438,0.00009409474,0.0001427067,0.001727743,0.00332265,0.9819333,0.00002292999],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001738413,0.998576,0.0001147192,0.0002305596,0.0001074731,0.000002091974,0.00002184149,0.000005336666,0.0007680425],"genre_scores_gemma":[0.001405355,0.9976346,0.0001300983,0.0001474948,0.0001017967,0.00000342617,0.00003892307,0.000001289219,0.0005369228],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002262331,"threshold_uncertainty_score":0.00756824,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03727511426020277,"score_gpt":0.3122842079654928,"score_spread":0.27500909370529,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}