{"id":"W2985354612","doi":"10.3390/genes10110932","title":"Cell-Specific DNA Methylation Signatures in Asthma","year":2019,"lang":"en","type":"review","venue":"Genes","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Chicoutimi","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Epigenetics; DNA methylation; Biology; Epigenomics; Methylation; Genetics; Immune system; Phenotype; Genome-wide association study; Immunology; Asthma; Cell type; DNA; Gene; Cell; Genotype; Gene expression; Single-nucleotide polymorphism","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002795802,0.0003288425,0.0006152318,0.0001681843,0.00003324038,0.00003533681,0.0002426077,0.0006678895,0.00004219881],"category_scores_gemma":[0.00001809623,0.000294356,0.0002936923,0.0001830713,0.00002283433,0.00000233126,0.0001023183,0.0001757747,0.00007520813],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002845116,"about_ca_system_score_gemma":0.0001272353,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004202464,"about_ca_topic_score_gemma":0.000007438316,"domain_scores_codex":[0.9984099,0.0001965133,0.000434203,0.0005631261,0.0001512487,0.0002449912],"domain_scores_gemma":[0.9991231,0.00003427379,0.0002378465,0.0005063348,0.00005041804,0.00004804273],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000005582461,0.00003313979,0.00001106207,0.001796842,0.00002829111,0.000002313021,0.00001074826,0.0001709156,0.0129183,0.00002410507,0.0009461599,0.9840525],"study_design_scores_gemma":[0.0001302836,0.00007343133,0.00002621874,0.0003041813,0.00004081879,6.175135e-7,0.000004466502,0.000004066067,0.01171005,0.00003150648,0.9873462,0.0003281539],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007869999,0.9964905,0.0002824313,0.000004253221,0.0004652887,0.0004953428,0.00003003018,0.000008196317,0.001436903],"genre_scores_gemma":[0.0003015834,0.9963644,0.0005333246,0.00001060745,0.0004729316,0.00004801603,0.0007585221,0.00006247447,0.001448177],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9864001,"threshold_uncertainty_score":0.9999509,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03727511426020277,"score_gpt":0.3122842079654928,"score_spread":0.27500909370529,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}