{"id":"W2985371900","doi":"10.1371/journal.pgen.1008486","title":"CRL4 regulates recombination and synaptonemal complex aggregation in the Caenorhabditis elegans germline","year":2019,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of British Columbia; National Science Foundation","keywords":"Biology; Synaptonemal complex; Meiosis; Homologous recombination; Synapsis; Caenorhabditis elegans; Homologous chromosome; Genetics; Genetic recombination; Ectopic recombination; Chromosomal crossover; Chromosome segregation; Cell biology; RAD51; Recombination; Chromosome; DNA; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008271133,0.0005523302,0.0001794294,0.0004668914,0.0003805435,0.0003601644,0.0004041096,0.0004264399,0.001031125],"category_scores_gemma":[0.0001194259,0.0002714021,0.0002611119,0.0001074915,0.000298386,0.0001727016,0.0003836406,0.0004799142,0.0005059258],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009934566,"about_ca_system_score_gemma":0.0004450792,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005668215,"about_ca_topic_score_gemma":0.008323796,"domain_scores_codex":[0.9998584,0.000009199673,0.00001021919,0.00004387834,0.00003620597,0.00004201853],"domain_scores_gemma":[0.9997917,0.00001102388,0.0000705051,0.00001499519,0.00003160481,0.00008015046],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008403447,0.00001713838,0.0003974375,0.00001943116,0.000005531843,0.0001045432,0.000009945037,0.000090766,0.9986082,0.00006629781,0.00008077686,0.0005159725],"study_design_scores_gemma":[0.00009013145,0.000159967,0.05287172,0.00002545652,0.00005360466,0.0003905764,0.0001059155,0.005148706,0.9363579,0.0001436708,0.004627454,0.00002508784],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949681,0.001119041,0.001274175,0.00008861149,0.0000329867,0.0000193296,0.0004271848,0.0002015826,0.001869081],"genre_scores_gemma":[0.9922717,0.0003485894,0.0009504273,0.00005511573,0.000004934804,0.00002903273,0.0004254368,0.0000454594,0.005869359],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005668215,"threshold_uncertainty_score":0.01127046,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01224775144442773,"score_gpt":0.227876405288602,"score_spread":0.2156286538441742,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}