{"id":"W2985412358","doi":"10.1016/j.neubiorev.2019.10.013","title":"Microglial memory of early life stress and inflammation: Susceptibility to neurodegeneration in adulthood","year":2019,"lang":"en","type":"review","venue":"Neuroscience & Biobehavioral Reviews","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":69,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Center for Advancing Translational Sciences; National Institute of Neurological Disorders and Stroke; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Neurodegeneration; Inflammation; Neuroscience; Microglia; Psychology; Developmental psychology; Medicine; Disease; Immunology; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005092393,0.001060252,0.001626032,0.001264924,0.0002221804,0.001016487,0.0007426437,0.001088131,0.002266219],"category_scores_gemma":[0.0006175608,0.0001894824,0.0003050489,0.001473309,0.0004756861,0.000839824,0.0006536009,0.001277275,0.001284643],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000479873,"about_ca_system_score_gemma":0.001020046,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00195996,"about_ca_topic_score_gemma":0.002946121,"domain_scores_codex":[0.9998935,0.00001737557,0.00001592378,0.00002388843,0.00003436062,0.00001489714],"domain_scores_gemma":[0.9997819,0.00008838243,0.00004477898,0.000006197342,0.00005583447,0.00002288515],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001313246,0.00006230802,0.0005115657,0.01069787,0.00009366718,0.0001676257,0.00007543853,0.0002993576,0.001965876,0.00291328,0.02217225,0.9609095],"study_design_scores_gemma":[0.00004550252,0.0002474813,0.007181257,0.01034211,0.0003130259,0.001951789,0.00025496,0.0001417419,0.0007068688,0.006876913,0.9718831,0.0000551253],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009917496,0.9992347,0.00004893507,0.0001529608,0.00007934648,0.000002152266,0.00001628855,0.00000282773,0.0003636001],"genre_scores_gemma":[0.0005277006,0.9990057,0.00005834832,0.00007035406,0.0001095127,0.000003942445,0.00001589672,4.327895e-7,0.0002081644],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002266219,"threshold_uncertainty_score":0.007581294,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1661706767062295,"score_gpt":0.3785485389922876,"score_spread":0.2123778622860582,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}