{"id":"W2985439614","doi":"10.1016/j.str.2019.10.014","title":"Molecular Basis for the PZP Domain of BRPF1 Association with Chromatin","year":2019,"lang":"en","type":"article","venue":"Structure","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health","keywords":"PHD finger; Chromatin; Histone acetyltransferase; Nucleosome; Histone; Chemistry; Zinc finger; Cell biology; DNA; Histone H3; Biophysics; Genetics; Biology; Biochemistry; Gene; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008102104,0.0000915812,0.0001029437,0.00001066085,0.00003603416,0.00001238253,0.0001484178,0.0001174709,0.00002637044],"category_scores_gemma":[0.00002594977,0.00006017486,0.00006211786,0.00004455498,0.00001848742,0.000001217896,0.00003247658,0.00004775308,8.987288e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001975981,"about_ca_system_score_gemma":0.00004358313,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006457821,"about_ca_topic_score_gemma":0.00002755944,"domain_scores_codex":[0.9994962,0.0000166751,0.0001082138,0.0001486473,0.0001035192,0.0001266976],"domain_scores_gemma":[0.999471,0.0000206565,0.0001435841,0.0002712684,0.00007632061,0.00001717861],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003621161,0.000005536253,0.004888487,0.00003693669,0.0001231985,1.529176e-7,0.00006665816,0.001268096,0.992238,0.0007325141,0.0002981295,0.0003061189],"study_design_scores_gemma":[0.001738292,0.0006638645,0.02911193,0.00003091295,0.0001115361,0.00001392648,0.0004829158,0.001609166,0.9487259,0.00310475,0.01403395,0.00037282],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969055,0.0001477885,0.001908521,0.0001786796,0.000087452,0.0003084175,0.0001403631,0.000003223038,0.0003200408],"genre_scores_gemma":[0.9956273,0.000008511642,0.00386557,0.0001364882,0.00005412312,0.000009156752,0.00009324012,0.00001734075,0.0001882225],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04351202,"threshold_uncertainty_score":0.2453859,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.001461221691517453,"score_gpt":0.1844496572796926,"score_spread":0.1829884355881752,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}