{"id":"W2985439614","doi":"10.1016/j.str.2019.10.014","title":"Molecular Basis for the PZP Domain of BRPF1 Association with Chromatin","year":2019,"lang":"en","type":"article","venue":"Structure","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health","keywords":"PHD finger; Chromatin; Histone acetyltransferase; Nucleosome; Histone; Chemistry; Zinc finger; Cell biology; DNA; Histone H3; Biophysics; Genetics; Biology; Biochemistry; Gene; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001922079,0.0002823278,0.0003520372,0.0001807313,0.0004567132,0.0004706736,0.0006434942,0.0006864213,0.003052127],"category_scores_gemma":[0.0004205095,0.0003232555,0.0003398238,0.0001524931,0.0004870816,0.0005378305,0.0004984748,0.0009979407,0.001101173],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004386904,"about_ca_system_score_gemma":0.0002295373,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007369347,"about_ca_topic_score_gemma":0.0004662403,"domain_scores_codex":[0.9998798,0.00001223413,0.000006786736,0.00004279833,0.00003185833,0.00002643925],"domain_scores_gemma":[0.9998143,0.00005997566,0.00003347425,0.00003097894,0.00001588632,0.00004535986],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000209402,0.00002718964,0.0007173417,0.00005745626,0.000005658218,0.0002246568,0.00002383853,0.0004031009,0.9949751,0.001814592,0.00009231987,0.001449397],"study_design_scores_gemma":[0.00005019995,0.00008072196,0.0185955,0.000008999137,0.000009123678,0.0007919158,0.00005040758,0.007707506,0.9686637,0.001398424,0.00262888,0.00001467325],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9776333,0.0009475785,0.01728921,0.000706228,0.00005707511,0.00003033367,0.0004767765,0.0003010854,0.002558302],"genre_scores_gemma":[0.9954383,0.0001289616,0.002823359,0.00007256783,0.00001200274,0.00001571096,0.0004108143,0.00002018274,0.001078058],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003052127,"threshold_uncertainty_score":0.01021034,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.001461221691517453,"score_gpt":0.1844496572796926,"score_spread":0.1829884355881752,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}