{"id":"W2985489262","doi":"","title":"ABERRANT METABOLIC AND SIGNALING PATHWAYS UNDERLIE IMPAIRED STEM CELL FUNCTION IN HUMAN OBESITY","year":2019,"lang":"en","type":"dissertation","venue":"MacSphere (McMaster University)","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; McMaster University","keywords":"Stem cell; Neuroscience; Signal transduction; Obesity; Function (biology); Biology; Cell biology; Medicine; Bioinformatics; Endocrinology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001370223,0.0004481099,0.0008752184,0.0004429817,0.000145858,0.00003633657,0.0001539442,0.0005187392,0.007039401],"category_scores_gemma":[0.00000256706,0.0004803771,0.0001880157,0.0004450094,0.0000375544,0.0002275891,0.00005851638,0.0005932429,0.00007664297],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001251097,"about_ca_system_score_gemma":0.0001801451,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003246813,"about_ca_topic_score_gemma":0.0005072008,"domain_scores_codex":[0.9981893,0.0001183955,0.0003243216,0.0006564712,0.0003008847,0.0004106643],"domain_scores_gemma":[0.9990696,0.00003350755,0.000262932,0.0003290677,0.00009803647,0.0002068621],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.004091834,0.001368344,0.03729518,0.005327505,0.001207622,0.001660455,0.01557502,0.0001017912,0.2532485,0.008400478,0.0006859879,0.6710373],"study_design_scores_gemma":[0.02791096,0.001813865,0.318686,0.002956059,0.009680366,0.00006892995,0.07374626,0.0003067155,0.05361316,0.0005613495,0.507136,0.003520345],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7962217,0.003149224,0.00007366506,0.00001273586,0.0004172165,0.0007334684,0.00001584124,0.00008533736,0.1992908],"genre_scores_gemma":[0.5716425,0.0001788615,0.00005221384,0.00004863922,0.00008207221,0.000001204445,0.0002490042,0.00004907842,0.4276964],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6675169,"threshold_uncertainty_score":0.9997648,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02086425353653991,"score_gpt":0.2157447770422218,"score_spread":0.1948805235056819,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}