{"id":"W2985715279","doi":"10.25251/skin.3.supp.15","title":"Tapinarof Cream for the Treatment of Plaque Psoriasis: Efficacy and Safety by Baseline Disease Characteristics and Skin Type in a Phase 2b Randomized Study","year":2019,"lang":"en","type":"article","venue":"SKIN The Journal of Cutaneous Medicine","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Probity Medical Research; University of British Columbia","funders":"","keywords":"Plaque psoriasis; Medicine; Dermatology; Randomized controlled trial; Psoriasis; Disease; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002299232,0.002196294,0.004050664,0.0005286774,0.0004997901,0.001393873,0.001165917,0.001855821,0.008017661],"category_scores_gemma":[0.001959677,0.001056919,0.001929948,0.0006432505,0.001494331,0.001597982,0.0004820528,0.003736055,0.001081363],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007704246,"about_ca_system_score_gemma":0.001268898,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001035873,"about_ca_topic_score_gemma":0.001768706,"domain_scores_codex":[0.9990771,0.0004457268,0.00004316201,0.0001599602,0.0001071377,0.000166924],"domain_scores_gemma":[0.9984975,0.0004755594,0.0002754937,0.0001601233,0.0001165461,0.0004748626],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9732032,0.01079745,0.0005228531,0.0003686582,0.0006460733,0.00002913779,0.00003996387,0.0002107844,0.003092709,0.00006780317,0.0004403449,0.01058094],"study_design_scores_gemma":[0.9141771,0.08202711,0.002335377,0.00002402382,0.0004071771,0.00003167961,0.00001776115,0.0002669397,0.0002736596,0.000106748,0.0003169529,0.00001549475],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888509,0.004239521,0.000606861,0.0003921649,0.0002449521,0.002989908,0.00122969,0.00009529003,0.001350619],"genre_scores_gemma":[0.9848663,0.004244615,0.001653963,0.0008622184,0.0005583117,0.003609461,0.001468165,0.00005348673,0.002683575],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008017661,"threshold_uncertainty_score":0.02682173,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01113033603718296,"score_gpt":0.2734871879888043,"score_spread":0.2623568519516214,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}