{"id":"W2985794754","doi":"10.1021/acs.jnatprod.9b00512","title":"Flavipesines A and B and Asperchalasines E–H: Cytochalasans and Merocytochalasans from <i>Aspergillus flavipes</i>","year":2019,"lang":"en","type":"article","venue":"Journal of Natural Products","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Natural Science Foundation of Hubei Province; Huazhong University of Science and Technology; Ministry of Education of the People's Republic of China; Tongji Medical College, Huazhong University of Science and Technology; National Natural Science Foundation of China","keywords":"Stereochemistry; Ring (chemistry); Isocitrate dehydrogenase; Chemistry; Aspergillus; Biology; Enzyme; Botany; Biochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003398288,0.0003299248,0.000775498,0.00022012,0.00009079342,0.00008169247,0.0001027812,0.0001642285,0.00003210246],"category_scores_gemma":[0.0005546444,0.0002111677,0.00007844323,0.0002563628,0.0002084163,0.0004511318,0.0001150462,0.0006181647,0.000007614245],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003604676,"about_ca_system_score_gemma":0.00008231985,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005403558,"about_ca_topic_score_gemma":0.00001039729,"domain_scores_codex":[0.9982733,0.00006015431,0.0005193923,0.0005053009,0.000345498,0.0002963125],"domain_scores_gemma":[0.9985382,0.0001338621,0.0003172607,0.0002617953,0.0005489099,0.0001999521],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006848419,0.00006412767,0.003286476,0.0002679383,0.0001773278,0.0001082645,0.0003641734,3.23031e-7,0.9814377,0.00005447224,0.001422997,0.01213135],"study_design_scores_gemma":[0.007380204,0.002133927,0.2316912,0.001649637,0.001163427,0.01526879,0.0007137132,0.0001453339,0.7031996,0.0007819087,0.03480876,0.001063489],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9445193,0.03252847,0.000001173065,0.0217153,0.0006667636,0.0004322917,0.00001465189,0.00002129709,0.0001007663],"genre_scores_gemma":[0.9916979,0.003185152,0.002259858,0.0006818848,0.001182468,2.971321e-7,0.000006848354,0.00003177423,0.000953834],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2782381,"threshold_uncertainty_score":0.8611168,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007188837102462425,"score_gpt":0.2186740095183256,"score_spread":0.2114851724158632,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}