{"id":"W2985858719","doi":"10.3389/fcvm.2019.00167","title":"SS-31 Peptide Reverses the Mitochondrial Fragmentation Present in Fibroblasts From Patients With DCMA, a Mitochondrial Cardiomyopathy","year":2019,"lang":"en","type":"article","venue":"Frontiers in Cardiovascular Medicine","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Libin Cardiovascular Institute of Alberta; St. Boniface Hospital; Alberta Children's Hospital; University of Manitoba; University of Calgary","funders":"Alberta Children's Hospital Foundation; Children's Hospital Foundation; Children's Cardiomyopathy Foundation; University of Calgary","keywords":"Cardiolipin; Mitochondrion; Cardiomyopathy; Inner mitochondrial membrane; Medicine; Pathology; Cell biology; Biology; Internal medicine; Heart failure; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003188467,0.0003389396,0.0007319273,0.0001920863,0.00006138366,0.00001968793,0.0003343167,0.0002814562,0.00007708051],"category_scores_gemma":[0.0001898474,0.0002391729,0.0003467631,0.0003391194,0.0001930671,0.00001968131,0.0001091625,0.0003235394,0.00002417118],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009711259,"about_ca_system_score_gemma":0.000104298,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006880284,"about_ca_topic_score_gemma":0.0001641849,"domain_scores_codex":[0.9970999,0.0004908302,0.0004733011,0.0008532962,0.000665403,0.0004173185],"domain_scores_gemma":[0.9985151,0.00004587161,0.0001294986,0.001087013,0.0001179834,0.0001044845],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.006390274,0.0002392602,0.7247094,0.00008844637,0.002226898,0.0001031111,0.001665736,0.01412577,0.04600375,0.0000110658,0.1970901,0.00734615],"study_design_scores_gemma":[0.04324454,0.002349888,0.2419865,0.0005420953,0.0006913463,0.00003021278,0.002481732,0.0002685346,0.006217806,0.0002310505,0.7007531,0.001203149],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9547566,0.008685225,0.01557172,0.0003001796,0.01684889,0.00233434,0.0000617233,0.00002187112,0.001419446],"genre_scores_gemma":[0.9352997,0.001289852,0.0292876,0.001946122,0.01892293,0.001058427,0.005403785,0.0003213697,0.006470194],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5036629,"threshold_uncertainty_score":0.9753188,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004949687750100628,"score_gpt":0.2022168801659883,"score_spread":0.1972671924158877,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}