{"id":"W2985902758","doi":"10.1111/imm.13153","title":"Ectopic germline recombination activity of the widely used Foxp3‐YFP‐Cre mouse: a case report","year":2019,"lang":"en","type":"article","venue":"Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; Canadian Diabetes Association","keywords":"Biology; Transgene; Genetics; Genotyping; Germline; Homologous recombination; Molecular biology; Genotype; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004338081,0.0003264765,0.0006827936,0.0001860682,0.0002431677,0.00001070618,0.0005650654,0.0007942997,0.001260865],"category_scores_gemma":[0.0002030511,0.0002492678,0.0002768819,0.0003083263,0.0007710436,0.00015179,0.0003920769,0.0008520145,0.0006638351],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001011355,"about_ca_system_score_gemma":0.0001766135,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000937279,"about_ca_topic_score_gemma":0.0001878591,"domain_scores_codex":[0.9974236,0.0006773401,0.0006853944,0.0005730545,0.00005798891,0.0005826277],"domain_scores_gemma":[0.997407,0.0003271421,0.0006918911,0.001367674,0.0001903703,0.00001597553],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000226898,0.0003752872,0.003884405,0.00002663704,0.0004375265,0.00046193,0.0003022366,0.000004982645,0.9893346,0.001381697,0.0004511737,0.003112642],"study_design_scores_gemma":[0.00325098,0.0005007714,0.005513063,0.00002680554,0.00008235177,0.02827517,0.0002003409,0.000007546478,0.9431403,0.0004555276,0.01824567,0.0003015296],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913319,0.001562715,0.0000693747,0.001117427,0.003809754,0.0006390295,0.00002514969,0.0001195485,0.001325078],"genre_scores_gemma":[0.9698328,0.00005597459,0.00003284989,0.00009233324,0.00002563399,0.00003718244,0.00006372746,0.00003462936,0.02982488],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04619434,"threshold_uncertainty_score":0.9999959,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01268672269676143,"score_gpt":0.2367000522877008,"score_spread":0.2240133295909393,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}