{"id":"W2986014667","doi":"10.3390/molecules24224141","title":"Application of N-Dodecyl l-Peptide to Enhance Serum Stability while Maintaining Inhibitory Effects on Myometrial Contractions Ex Vivo","year":2019,"lang":"en","type":"article","venue":"Molecules","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Fonds de recherche du Québec – Nature et technologies; Canadian Institutes of Health Research; Université de Montréal; Centre in Green Chemistry and Catalysis","keywords":"Ex vivo; Chemistry; Peptide; In vivo; Myometrium; Serine protease; Biochemistry; Protease; In vitro; Biology; Endocrinology; Enzyme; Uterus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002444078,0.0003684077,0.0001943232,0.00009098736,0.0001077118,0.0001497067,0.0001242912,0.0002287314,0.0008362525],"category_scores_gemma":[0.0001884108,0.00009543494,0.0001406689,0.0001043387,0.0001732383,0.000148599,0.0001344944,0.0003949342,0.0002229724],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000191109,"about_ca_system_score_gemma":0.0002395404,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000319875,"about_ca_topic_score_gemma":0.0005534685,"domain_scores_codex":[0.9998916,0.00002562131,0.00001410002,0.00002474782,0.00002114731,0.00002284547],"domain_scores_gemma":[0.9998417,0.00003623732,0.00005039799,0.00001985878,0.00002501996,0.00002677237],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008072548,0.00001103473,0.00002524647,0.00001130505,0.000001213924,0.00001273626,0.000005077867,0.00001562427,0.9994197,0.00001197382,0.000005968213,0.0003993445],"study_design_scores_gemma":[0.000006739937,0.0001465152,0.000210261,0.000001084119,0.000003459253,0.00003848401,0.000003176206,0.0001099491,0.9990184,0.000003465123,0.0004575503,9.09973e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941883,0.0009675215,0.003730466,0.00008916316,0.00002548178,0.00005800331,0.0001083564,0.00004451537,0.0007881381],"genre_scores_gemma":[0.9922807,0.0007156442,0.00499954,0.00007478634,0.00001296109,0.00005673694,0.0001851266,0.00002117637,0.001653353],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008362525,"threshold_uncertainty_score":0.002797544,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005769290054718428,"score_gpt":0.2512736303840817,"score_spread":0.2455043403293632,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}