{"id":"W2986233775","doi":"10.1002/acn3.50938","title":"Study partner‐reported decline identifies cognitive decline and dementia risk","year":2019,"lang":"en","type":"article","venue":"Annals of Clinical and Translational Neurology","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Aging; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; Genentech; National Institutes of Health; Takeda Pharmaceutical Company; IXICO; H. Lundbeck A/S; Servier; Eisai; Northern California Institute for Research and Education; Pfizer; Biogen; BioClinica; F. Hoffmann-La Roche; Roche; University of Southern California; Novartis Pharmaceuticals Corporation; U.S. Department of Defense; Eli Lilly and Company; Bristol-Myers Squibb; Alzheimer's Drug Discovery Foundation; AbbVie; Fujirebio Europe; Alzheimer's Association; Foundation for the National Institutes of Health; GE Healthcare; Alzheimer's Disease Neuroimaging Initiative; Meso Scale Diagnostics","keywords":"Dementia; Cognitive decline; Medicine; Neuropsychology; Cognition; Gerontology; Disease; Effects of sleep deprivation on cognitive performance; Cognitive test; Clinical psychology; Psychiatry; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001689925,0.0001370843,0.0005333757,0.0001052733,0.0000589841,0.00001457024,0.00005139104,0.0001079463,0.0003581262],"category_scores_gemma":[0.0005261,0.0001110735,0.0001326804,0.0001126808,0.0003715358,0.00009195861,0.00009040617,0.0003394472,0.00001912081],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":7.074105e-8,"about_ca_system_score_gemma":0.0000662465,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003265134,"about_ca_topic_score_gemma":0.00006459292,"domain_scores_codex":[0.9976023,0.0003837808,0.0009466066,0.0004427092,0.0004057791,0.0002188072],"domain_scores_gemma":[0.9975445,0.001517582,0.0002240729,0.0001192897,0.0004194034,0.0001751894],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003366875,0.001219342,0.9785346,0.00003656492,0.0007318583,0.00007708512,0.0000528895,7.913876e-7,0.00002865711,0.0001166573,0.000033486,0.01580121],"study_design_scores_gemma":[0.006419086,0.003882256,0.983988,0.000016999,0.0004483489,0.00003727433,0.00004721811,0.0001925573,0.000136616,0.004122331,0.0006233774,0.00008593134],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913763,0.0004973653,0.00007808612,0.006208865,0.0001001753,0.0007427747,0.00003572003,0.00001510251,0.0009455518],"genre_scores_gemma":[0.9960582,0.001104008,0.0000336341,0.002483752,0.0000835555,0.00001516952,0.00005448279,0.000010831,0.0001564302],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01571528,"threshold_uncertainty_score":0.4529447,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1385988545632994,"score_gpt":0.4686302692329011,"score_spread":0.3300314146696016,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}