{"id":"W2986450192","doi":"10.1002/smll.201902347","title":"An Investigation of PS‐ <i>b</i> ‐PEO Polymersomes for the Oral Treatment and Diagnosis of Hyperammonemia","year":2019,"lang":"en","type":"article","venue":"Small","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"NeuroRx Research (Canada)","funders":"Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Polymersome; Hyperammonemia; Chemistry; Urea cycle; Ethylene glycol; Vesicle; Pharmacology; Chromatography; Biochemistry; Amphiphile; Medicine; Arginine; Copolymer; Membrane; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001363011,0.0002342376,0.000127537,0.0001255508,0.0000644869,0.0001273908,0.00008113134,0.0002949926,0.000442609],"category_scores_gemma":[0.0001898443,0.00007746368,0.0001073664,0.00005459969,0.0001280576,0.0002318141,0.00009031354,0.0001960402,0.00008957771],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009394636,"about_ca_system_score_gemma":0.00009353954,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001615164,"about_ca_topic_score_gemma":0.0002601659,"domain_scores_codex":[0.9999571,0.0000128883,0.000002183072,0.00001010133,0.000009622459,0.000008181612],"domain_scores_gemma":[0.999923,0.00003003269,0.00001918075,0.000004085507,0.00001096409,0.00001268469],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001191234,0.00001592635,0.00008934143,0.00003831513,0.000002856786,0.00004419703,0.000006235202,0.00002934659,0.9971532,0.00002294944,0.00001479499,0.002463718],"study_design_scores_gemma":[0.00001684092,0.001131628,0.002087329,0.000007217382,0.00002262467,0.0003848505,0.00001404242,0.0006050771,0.9944504,0.00002224987,0.001253992,0.000003661133],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910944,0.002125235,0.004805369,0.0001671267,0.00002514688,0.00006561286,0.0001088824,0.00004641144,0.001561774],"genre_scores_gemma":[0.9928414,0.00140521,0.004398465,0.00007320786,0.00001133615,0.00004489457,0.00008799441,0.000009634824,0.001127782],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000442609,"threshold_uncertainty_score":0.001480639,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01295988453156368,"score_gpt":0.2393947576119537,"score_spread":0.22643487308039,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}