{"id":"W2986450192","doi":"10.1002/smll.201902347","title":"An Investigation of PS‐ <i>b</i> ‐PEO Polymersomes for the Oral Treatment and Diagnosis of Hyperammonemia","year":2019,"lang":"en","type":"article","venue":"Small","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"NeuroRx Research (Canada)","funders":"Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Polymersome; Hyperammonemia; Chemistry; Urea cycle; Ethylene glycol; Vesicle; Pharmacology; Chromatography; Biochemistry; Amphiphile; Medicine; Arginine; Copolymer; Membrane; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006312919,0.00006277511,0.00009615019,0.00001183975,0.00001589447,0.000003928239,0.00006638591,0.00004427524,0.000007717354],"category_scores_gemma":[0.000008513101,0.0000422616,0.00003808742,0.00002412682,0.00006215072,0.000001329411,0.00001327584,0.000009104631,4.282588e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":6.741876e-7,"about_ca_system_score_gemma":0.00002698442,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000135516,"about_ca_topic_score_gemma":0.0001092434,"domain_scores_codex":[0.9996631,0.00002063172,0.00009372065,0.0001213759,0.00002920056,0.00007193908],"domain_scores_gemma":[0.9996868,0.00002084517,0.00005065662,0.0001892941,0.00002552299,0.00002690375],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008391147,0.00005541777,0.3984567,0.00004127799,0.00007447197,2.624963e-8,0.000279572,0.00004598013,0.5561716,0.0002018132,0.0001376273,0.04445164],"study_design_scores_gemma":[0.0009635928,0.0007286644,0.0703573,0.000005138712,0.00006942129,5.538744e-7,0.0003180371,0.00006007845,0.9195381,0.0001282124,0.007750335,0.00008055592],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954791,0.003905623,0.00006103626,0.0001024757,0.00005839808,0.0002944793,0.00003088884,0.000001431,0.00006655852],"genre_scores_gemma":[0.9979216,0.001015302,0.0006597164,0.00009989196,0.00002660445,0.00005970234,0.00004884374,0.000006877667,0.0001614175],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3633665,"threshold_uncertainty_score":0.1723378,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01295988453156368,"score_gpt":0.2393947576119537,"score_spread":0.22643487308039,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}