{"id":"W2986454336","doi":"10.1080/21645515.2019.1689081","title":"A dendritic cell-targeted chimeric hepatitis B virus immunotherapeutic vaccine induces both cellular and humoral immune responses<i>in vivo</i>","year":2019,"lang":"en","type":"article","venue":"Human Vaccines & Immunotherapeutics","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; University of Alberta","funders":"National Research Council Canada; Canadian Institutes of Health Research","keywords":"Antigen; Hepatitis B virus; Immune system; Virology; Immunogenicity; Antibody; Immunology; HBsAg; Biology; Virus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001513708,0.0003374807,0.0003236669,0.0001284191,0.00008365607,0.0002222985,0.0001128292,0.000304343,0.0007639825],"category_scores_gemma":[0.00009240809,0.0001298281,0.0001848933,0.00007049674,0.0001714363,0.0001123854,0.0001228135,0.0005385741,0.0003591777],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002423835,"about_ca_system_score_gemma":0.0001728369,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001972149,"about_ca_topic_score_gemma":0.0002412947,"domain_scores_codex":[0.999827,0.00003310479,0.00001506832,0.00003791261,0.00003877764,0.00004824649],"domain_scores_gemma":[0.9999268,0.0000129344,0.0000172003,0.000009684834,0.00001350273,0.00001988371],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001552003,0.00007352133,0.00008278492,0.00002975529,0.000002418004,0.00001600535,0.000005862182,0.0000426039,0.998576,0.00003954515,0.00003506892,0.0009412727],"study_design_scores_gemma":[0.00006351748,0.002003264,0.001366807,0.000005079041,0.00001518181,0.0002140726,0.00001118646,0.0007463312,0.9937177,0.00002242992,0.001832029,0.000002424553],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925073,0.0007662416,0.003927705,0.00009949521,0.0000527203,0.0001430961,0.0002751194,0.0001445114,0.002083807],"genre_scores_gemma":[0.9942575,0.0004065116,0.002841461,0.00007087269,0.00001566847,0.00009131878,0.0004584999,0.00001509037,0.001843159],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007639825,"threshold_uncertainty_score":0.002555788,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01794394459657581,"score_gpt":0.2691184225617083,"score_spread":0.2511744779651324,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}