{"id":"W2986512634","doi":"10.1111/php.13174","title":"Strained, Photoejecting Ru(II) Complexes that are Cytotoxic Under Hypoxic Conditions","year":2019,"lang":"en","type":"article","venue":"Photochemistry and Photobiology","topic":"Nanoplatforms for cancer theranostics","field":"Engineering","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"Acadia University","funders":"National Institute of General Medical Sciences; National Cancer Institute; Canadian Institutes of Health Research","keywords":"Photobiology; Chemistry; Cytotoxicity; Ligand (biochemistry); Stereochemistry; Aromaticity; Medicinal chemistry; Photochemistry; Biophysics; Receptor; Biochemistry; In vitro; Molecule; Organic chemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00008327347,0.0003112526,0.0003723846,0.00005226161,0.0001682964,0.00002866295,0.0001903058,0.0002547936,0.001526617],"category_scores_gemma":[0.00001367041,0.0003131816,0.00008686758,0.0001196711,0.0001393093,0.0001002977,0.0000689895,0.0003291381,0.00004706512],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007720784,"about_ca_system_score_gemma":0.00002570026,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000218242,"about_ca_topic_score_gemma":0.00001750966,"domain_scores_codex":[0.9988778,0.00001203561,0.000244708,0.0003348593,0.00008440001,0.0004462345],"domain_scores_gemma":[0.9992884,0.0001533086,0.00008290883,0.0003255233,0.00003003657,0.0001197683],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002601739,0.00002129818,0.001764227,0.0001689461,0.00009846214,0.000005176585,0.0001066787,0.0003364593,0.9971115,0.00006678259,0.000257944,0.00003648943],"study_design_scores_gemma":[0.0009328132,0.00006964299,0.0009268179,0.00007515152,0.00002850142,0.0001551452,0.0005120236,0.0009318695,0.9920202,0.002015724,0.001904743,0.0004273361],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939409,0.0004552228,0.00009319149,0.00001752217,0.0003482581,0.0004971543,0.0003884103,0.0002864444,0.003972856],"genre_scores_gemma":[0.9987987,0.0001059013,0.00007993908,0.0001997789,0.00008957895,0.0001093024,0.0001924609,0.00004796916,0.0003764105],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005091288,"threshold_uncertainty_score":0.9999321,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0130001232767076,"score_gpt":0.2189037359294508,"score_spread":0.2059036126527432,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}