{"id":"W2986668917","doi":"10.1002/cmdc.201900465","title":"Proline‐Rich Peptides with Improved Antimicrobial Activity against <i>E. coli</i>, <i>K. pneumoniae</i>, and <i>A. baumannii</i>","year":2019,"lang":"en","type":"article","venue":"ChemMedChem","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Infection and Immunity; Università degli Studi di Trieste","keywords":"Antimicrobial; Antimicrobial peptides; Cytotoxicity; Mode of action; Proline; Chemistry; Biochemistry; Microbiology; Bacteria; Amino acid; Biology; In vitro","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001557934,0.0003454155,0.0002444989,0.0001471229,0.0000670391,0.0002097801,0.0001731207,0.0002181333,0.0008239457],"category_scores_gemma":[0.0001449944,0.00009125064,0.0001851957,0.000169465,0.0001460796,0.0002017399,0.0001605567,0.0004111246,0.0003109346],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001339567,"about_ca_system_score_gemma":0.0001183671,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001346857,"about_ca_topic_score_gemma":0.0002455539,"domain_scores_codex":[0.9998938,0.0000246928,0.00001174192,0.00001721614,0.00002635709,0.00002619731],"domain_scores_gemma":[0.9998912,0.00001777093,0.00004229902,0.000007857667,0.00001649997,0.00002443659],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006552399,0.00001963593,0.000206148,0.00005739568,0.000005281387,0.00005843747,0.00000715029,0.00009556788,0.9969602,0.00004174414,0.00001766129,0.002465436],"study_design_scores_gemma":[0.00001412295,0.001122288,0.00268863,0.000009649376,0.0000276379,0.0006273795,0.00001938854,0.0002357559,0.9924225,0.00002119182,0.002804997,0.000006471369],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928936,0.002823499,0.002579427,0.0000511086,0.00001878585,0.00004021067,0.0002840476,0.00003529463,0.001274052],"genre_scores_gemma":[0.988089,0.001428926,0.008582402,0.00008634965,0.000010825,0.00002232192,0.0006151236,0.00001476755,0.001150307],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008239457,"threshold_uncertainty_score":0.002756357,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006053815571935379,"score_gpt":0.1942075568397547,"score_spread":0.1881537412678193,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}