{"id":"W2986668917","doi":"10.1002/cmdc.201900465","title":"Proline‐Rich Peptides with Improved Antimicrobial Activity against <i>E. coli</i>, <i>K. pneumoniae</i>, and <i>A. baumannii</i>","year":2019,"lang":"en","type":"article","venue":"ChemMedChem","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Infection and Immunity; Università degli Studi di Trieste","keywords":"Antimicrobial; Antimicrobial peptides; Cytotoxicity; Mode of action; Proline; Chemistry; Biochemistry; Microbiology; Bacteria; Amino acid; Biology; In vitro","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001778267,0.0004907465,0.0006416111,0.00008933715,0.000263808,0.00007797362,0.0002725482,0.0003561594,0.0001128747],"category_scores_gemma":[0.00001962428,0.0004053437,0.0001130872,0.0001928803,0.0005246491,0.0003840083,0.0002129648,0.000580506,0.0003064737],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005463937,"about_ca_system_score_gemma":0.0001177608,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005371291,"about_ca_topic_score_gemma":0.00002250825,"domain_scores_codex":[0.9980886,0.00006483094,0.0002891888,0.000743215,0.00005937216,0.000754797],"domain_scores_gemma":[0.9990091,0.0001192518,0.000231577,0.0004605662,0.0001118517,0.00006765132],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004199286,0.0002066088,0.003268237,0.0001536072,0.0001698279,0.000006638063,0.000299967,0.000005100867,0.9869167,0.00004277735,0.00693031,0.001580266],"study_design_scores_gemma":[0.002433358,0.0002440951,0.001257628,0.0001260083,0.00005214566,0.0001410077,0.0001912062,0.00001750138,0.9826189,0.00001282458,0.0123213,0.0005840337],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899744,0.0002902595,0.00003778836,0.0007501399,0.0003369339,0.0007052121,0.0000760277,0.0002002541,0.00762899],"genre_scores_gemma":[0.9888588,0.0001728466,0.0002311001,0.001274428,0.00008700507,0.00003333878,0.000103477,0.00007160168,0.009167457],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005390991,"threshold_uncertainty_score":0.9998398,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006053815571935379,"score_gpt":0.1942075568397547,"score_spread":0.1881537412678193,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}