{"id":"W2986700515","doi":"10.1056/nejmoa1912388","title":"Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction","year":2019,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2967,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Heart Institute","funders":"Canadian Institutes of Health Research; Abbott Vascular; Esperion Therapeutics; Heart Research Institute; Bausch Health; Duke Clinical Research Institute; Eisai; Daiichi Sankyo Europe; Gilead Sciences; Servier; University of Glasgow; AstraZeneca; Amarin Corporation; Singulex; Ionis Pharmaceuticals; TG Therapeutics; Massachusetts Medical Society; Boston Scientific Corporation; Kowa Company; Sanofi; Institut de Cardiologie de Montréal; Celgene; Pfizer; Biogen; GlaxoSmithKline; Amgen; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Colchicine; Gout; Medicine; Pericarditis; Myocardial infarction; Inflammation; Pharmacology; Internal medicine; Cardiology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001117506,0.0003797685,0.001357899,0.000224753,0.0002165936,0.0005240803,0.0003430726,0.0007126297,0.002762786],"category_scores_gemma":[0.002785578,0.0001038069,0.000614104,0.0002194272,0.0004148615,0.0002651603,0.00019155,0.001136048,0.0003011947],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004909725,"about_ca_system_score_gemma":0.0003745037,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003085866,"about_ca_topic_score_gemma":0.0005374472,"domain_scores_codex":[0.9993691,0.0003801664,0.00006029434,0.00005902752,0.00007849165,0.00005289134],"domain_scores_gemma":[0.9978654,0.0008234248,0.0007250321,0.0000733588,0.0001175126,0.0003952761],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7962355,0.007076416,0.01660911,0.002555603,0.001564584,0.0002040897,0.00008281946,0.0005050984,0.01803085,0.0001465902,0.001329524,0.1556598],"study_design_scores_gemma":[0.3425829,0.4822065,0.1557006,0.000551472,0.00280087,0.0007923645,0.0001132764,0.001742589,0.009814729,0.0003392433,0.003293241,0.00006211258],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9743276,0.02238887,0.0003396724,0.0005462264,0.0001692489,0.0002674005,0.0003718672,0.00004387757,0.001545202],"genre_scores_gemma":[0.9964929,0.00230831,0.0002055525,0.000247084,0.0001916995,0.00009862009,0.0002434673,0.000003113427,0.0002091492],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002762786,"threshold_uncertainty_score":0.009242475,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003206773287188557,"score_gpt":0.219258100176237,"score_spread":0.2160513268890485,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}