{"id":"W2986852082","doi":"10.1182/blood.v128.22.1273.1273","title":"Argonaute 2 Silencing of Band 3 in Early Reticulocytes","year":2016,"lang":"en","type":"article","venue":"Blood","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Blood Services; University of Toronto","funders":"","keywords":"Argonaute; Reticulocyte; Gene silencing; Biology; Erythropoiesis; Molecular biology; RNA; RNA-induced silencing complex; microRNA; Cell biology; RNA interference; Gene; Genetics; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008500884,0.0000497458,0.0001538164,0.00007226338,0.00001148989,0.000001139652,0.00002599201,0.00006135982,0.0001668121],"category_scores_gemma":[0.0001507432,0.00003242631,0.00003623531,0.00007729721,0.00005410127,0.0000272249,0.000008545089,0.00004933269,0.00003695545],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001142267,"about_ca_system_score_gemma":0.00005277097,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004401508,"about_ca_topic_score_gemma":0.00001397385,"domain_scores_codex":[0.9995326,0.00002861464,0.0001400087,0.0001074417,0.00007426514,0.0001170734],"domain_scores_gemma":[0.9996585,0.00008406679,0.00003659821,0.0001327034,0.00004259541,0.00004555431],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001288186,0.0002024091,0.1464307,0.00004222678,0.00002142056,0.00003610406,0.0003681108,1.908858e-7,0.8509442,0.0003852931,0.0001105278,0.001330003],"study_design_scores_gemma":[0.004492228,0.0004754531,0.5488357,0.0003015488,0.00004153327,0.00002309203,0.00005261051,0.000001050464,0.4445238,0.0002260505,0.000962463,0.00006445993],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947332,0.0002165689,0.00004044999,0.0003215617,0.00008313904,0.00008409979,0.000002461676,0.00001891815,0.004499671],"genre_scores_gemma":[0.9985607,0.0001397857,0.0002430172,0.0001119986,0.0001031627,0.000004325391,0.000001092996,0.000006305326,0.0008296203],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4064204,"threshold_uncertainty_score":0.1826475,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01210490815739012,"score_gpt":0.2313061913708263,"score_spread":0.2192012832134362,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}