{"id":"W2986884289","doi":"10.1093/hmg/ddz259","title":"Defective cell adhesion function of solute transporter, SLC4A11, in endothelial corneal dystrophies","year":2019,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Corneal surgery and disorders","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; University of Alberta","funders":"National Medical Research Council; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Deutsche Forschungsgemeinschaft","keywords":"Cell adhesion; Cell biology; Biology; Cell adhesion molecule; HEK 293 cells; Transfection; Cell; Molecular biology; Cell culture; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007994233,0.0001433527,0.0002762819,0.0001505186,0.00002453313,0.000004800101,0.0000527526,0.0001004169,0.0001807809],"category_scores_gemma":[0.000005456669,0.0001461706,0.0001503964,0.0001483184,0.00005364555,0.00002075716,0.00001664198,0.0001331148,0.00002923762],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002608734,"about_ca_system_score_gemma":0.00004180561,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005110749,"about_ca_topic_score_gemma":0.000041883,"domain_scores_codex":[0.9989977,0.00004548279,0.0002870196,0.0002454939,0.0002151602,0.0002091315],"domain_scores_gemma":[0.9995226,0.00001952838,0.00008514644,0.0002501215,0.00005657843,0.00006604459],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0005056855,0.0002721521,0.0760314,0.0001506172,0.00002632737,0.00005971426,0.0002425185,0.0004095152,0.9208061,0.0001915917,0.00002805319,0.001276354],"study_design_scores_gemma":[0.004547922,0.002037228,0.715614,0.0001221245,0.0001996935,0.00001085771,0.0002085818,0.0002501654,0.274851,0.0009876085,0.0008837513,0.0002871161],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945934,0.0007562695,0.0008200145,0.00001286044,0.0001413256,0.0004105291,0.000008599249,0.00002111527,0.003235868],"genre_scores_gemma":[0.9993678,0.00008299201,0.000139873,0.0000996362,0.00002772981,0.000008347292,0.00004075097,0.0000268752,0.0002060445],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6459551,"threshold_uncertainty_score":0.5960664,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01011755335635621,"score_gpt":0.2265736062695352,"score_spread":0.2164560529131789,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}