{"id":"W2986884289","doi":"10.1093/hmg/ddz259","title":"Defective cell adhesion function of solute transporter, SLC4A11, in endothelial corneal dystrophies","year":2019,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Corneal surgery and disorders","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; University of Alberta","funders":"National Medical Research Council; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Deutsche Forschungsgemeinschaft","keywords":"Cell adhesion; Cell biology; Biology; Cell adhesion molecule; HEK 293 cells; Transfection; Cell; Molecular biology; Cell culture; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007440956,0.0002883859,0.0001275456,0.0002250079,0.0001859468,0.0001805072,0.0001193893,0.0003369562,0.0006617542],"category_scores_gemma":[0.0001253505,0.00009147053,0.0001995536,0.0001820547,0.0001968013,0.0001223908,0.0002212446,0.0001889374,0.0001437352],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002835023,"about_ca_system_score_gemma":0.0001371654,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001919764,"about_ca_topic_score_gemma":0.002086811,"domain_scores_codex":[0.9999403,0.000009163909,0.00000661874,0.00001287988,0.00002193493,0.000009122797],"domain_scores_gemma":[0.9999497,0.000007791882,0.00001855772,0.000003109483,0.000005797779,0.00001501287],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001216202,0.00001677427,0.004439311,0.00004668879,0.00003014768,0.001201408,0.00004048581,0.0002885555,0.9913179,0.0002147963,0.000184433,0.002097921],"study_design_scores_gemma":[0.0000463923,0.0002492736,0.1750555,0.00002152019,0.0001129234,0.01597662,0.0001744856,0.01206162,0.7905051,0.0004664715,0.005298645,0.00003155779],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980926,0.0003659902,0.001068589,0.00004014512,0.000006790057,0.000002646048,0.0001330537,0.00003538192,0.0002548874],"genre_scores_gemma":[0.9983795,0.0001941793,0.0007318213,0.00002556932,0.00000159906,0.000002945904,0.0001993449,0.000006390544,0.0004586517],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001919764,"threshold_uncertainty_score":0.003817141,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01011755335635621,"score_gpt":0.2265736062695352,"score_spread":0.2164560529131789,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}