{"id":"W2987096210","doi":"10.1002/anie.201912518","title":"Direct Catalytic Decarboxylative Amination of Aryl Acetic Acids","year":2019,"lang":"en","type":"article","venue":"Angewandte Chemie International Edition","topic":"Catalytic C–H Functionalization Methods","field":"Chemistry","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Amination; Decarboxylation; Nucleophile; Electrophile; Aryl; Organic chemistry; Isocyanate; Catalysis; Carboxylic acid; Oxidative decarboxylation; Amine gas treating; Combinatorial chemistry; Alkyl","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002607895,0.0001963293,0.0002427765,0.0001736478,0.00003790313,0.00003251343,0.000262967,0.0001542615,0.006791574],"category_scores_gemma":[0.0005233624,0.0002121009,0.0001474502,0.00023725,0.00008889886,0.0003992745,0.00008301668,0.0001520998,0.0001423439],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003521212,"about_ca_system_score_gemma":0.00008287692,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004084188,"about_ca_topic_score_gemma":0.000005836152,"domain_scores_codex":[0.9982955,0.000008861033,0.0004423453,0.0003822549,0.0007008993,0.0001701587],"domain_scores_gemma":[0.9983846,0.0003488483,0.00034781,0.0003088211,0.000542471,0.00006744182],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001125306,0.0001613273,0.007450464,0.0001532393,0.0001879144,0.000002993381,0.0003539307,0.0002341348,0.9853455,0.001625905,0.003112033,0.001260047],"study_design_scores_gemma":[0.0008105517,0.00002034944,0.003066328,0.0001287002,0.00005074826,0.00001493219,0.0001594268,0.0008748283,0.985536,0.0009051405,0.008226541,0.0002064755],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5152874,0.000194501,0.02233251,0.0008913095,0.004309746,0.0003490087,0.0006807431,0.0002913628,0.4556634],"genre_scores_gemma":[0.9874437,0.00003761294,0.0005464174,0.00008309467,0.00080264,0.00004153466,0.002836196,0.00003218311,0.008176621],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4721563,"threshold_uncertainty_score":0.9941164,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01493008024164902,"score_gpt":0.2773754503979644,"score_spread":0.2624453701563154,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}