{"id":"W2987106272","doi":"10.1016/j.exphem.2019.09.011","title":"3169 – ONCOGENE CONTRIBUTIONS IN A SYNTHETIC MODEL OF DE NOVO GENERATED HUMAN T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA","year":2019,"lang":"en","type":"article","venue":"Experimental Hematology","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency; University of British Columbia","funders":"","keywords":"Lymphoblastic Leukemia; Cancer research; Oncogene; Leukemia; Cell; Computational biology; Biology; Immunology; Genetics; Cell cycle","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001009803,0.0002422726,0.0001453832,0.000189451,0.0001843348,0.0002779143,0.0002688881,0.0002810018,0.001998232],"category_scores_gemma":[0.0001581867,0.0001077416,0.0001977898,0.000109589,0.0001993587,0.0001287066,0.0001626702,0.0003404751,0.000237641],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000322986,"about_ca_system_score_gemma":0.0002165026,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007978524,"about_ca_topic_score_gemma":0.0004131377,"domain_scores_codex":[0.9999167,0.00002651011,0.000003823145,0.00001411499,0.00002634709,0.00001258969],"domain_scores_gemma":[0.9999366,0.00002305609,0.00001703391,0.000008099766,0.000005554118,0.000009667175],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0003112074,0.0001481945,0.0003807455,0.00005382371,0.00001277167,0.0003561144,0.00004875281,0.03264418,0.943325,0.02085501,0.000174104,0.001690023],"study_design_scores_gemma":[0.0001814412,0.0008291362,0.001314381,0.000007717977,0.00004372653,0.0005464302,0.00007822285,0.2187906,0.7583855,0.005236153,0.01456579,0.00002089874],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9868478,0.0001674928,0.008379106,0.0001146171,0.00005201135,0.00003123156,0.0002652431,0.00005498268,0.004087609],"genre_scores_gemma":[0.9935575,0.0001216842,0.003145054,0.0000148848,0.000004823055,0.0000204593,0.0002130703,0.00002191853,0.00290056],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001998232,"threshold_uncertainty_score":0.00668478,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01449556875807287,"score_gpt":0.3156631821363769,"score_spread":0.301167613378304,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}