{"id":"W2987167874","doi":"10.1080/21645515.2019.1689080","title":"A dendritic cell receptor-targeted chimeric immunotherapeutic protein (C-HBV) for the treatment of chronic hepatitis B","year":2019,"lang":"en","type":"article","venue":"Human Vaccines & Immunotherapeutics","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Research Council Canada","keywords":"Hepatitis B virus; Granzyme B; T cell; Cytotoxic T cell; Immunology; Biology; IL-2 receptor; CD8; Virology; Antigen; Immune system; Virus; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005403895,0.0002235331,0.0001526048,0.00023336,0.0001800239,0.0003199129,0.0002329676,0.0004790862,0.00354352],"category_scores_gemma":[0.000407633,0.00008317158,0.000197145,0.0001560032,0.0003562628,0.0003191628,0.0001365342,0.0008122764,0.0005050226],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003199925,"about_ca_system_score_gemma":0.0005047274,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007431722,"about_ca_topic_score_gemma":0.0008236867,"domain_scores_codex":[0.9999301,0.00002759493,0.000005517313,0.00001045292,0.00001534706,0.00001093308],"domain_scores_gemma":[0.9997913,0.0001196595,0.00002454322,0.00001211984,0.0000292669,0.00002298303],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005934604,0.002387781,0.00614199,0.001756661,0.0001583308,0.0008784961,0.0001708838,0.001188426,0.6324051,0.01914857,0.00591625,0.3239128],"study_design_scores_gemma":[0.003677027,0.02513211,0.02064996,0.0003767452,0.0005252994,0.006489212,0.0003544831,0.00457151,0.715678,0.008816667,0.2136734,0.00005559218],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7745,0.1425792,0.02547511,0.01709205,0.001090465,0.0008469874,0.0006905906,0.0002091126,0.03751653],"genre_scores_gemma":[0.9077366,0.06632073,0.01365014,0.002318971,0.0003068312,0.0001551005,0.0006306479,0.00002598338,0.008855046],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00354352,"threshold_uncertainty_score":0.01185429,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02328464696187546,"score_gpt":0.2856325109459552,"score_spread":0.2623478639840797,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}