{"id":"W2987175987","doi":"10.1007/s00421-019-04259-7","title":"The impact of acute and chronic exercise on Nrf2 expression in relation to markers of mitochondrial biogenesis in human skeletal muscle","year":2019,"lang":"en","type":"article","venue":"European Journal of Applied Physiology","topic":"Exercise and Physiological Responses","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":false,"ca_institutions":"York University; Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"TFAM; Mitochondrial biogenesis; NRF1; SOD2; Citrate synthase; Skeletal muscle; Internal medicine; Endocrinology; Downregulation and upregulation; Mitochondrion; Biology; Endurance training; Chemistry; Andrology; Superoxide dismutase; Oxidative stress; Medicine; Cell biology; Gene; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002226086,0.0001884192,0.0003503092,0.0001533638,0.0002605697,0.0003059075,0.0001130865,0.0002826273,0.001559234],"category_scores_gemma":[0.0002775942,0.0001420039,0.000255899,0.0001947156,0.0003791875,0.0002435803,0.0002980994,0.0003243378,0.0001429825],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001395699,"about_ca_system_score_gemma":0.0001519132,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009439546,"about_ca_topic_score_gemma":0.001885495,"domain_scores_codex":[0.999869,0.00002870689,0.00001232801,0.00003995501,0.00001270049,0.00003735011],"domain_scores_gemma":[0.9998562,0.00004523963,0.00002624336,0.00001502777,0.00001965415,0.00003762929],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.05486919,0.001384695,0.05333027,0.0004770222,0.0002765048,0.0003302831,0.0005979439,0.0003707634,0.8699566,0.0001476547,0.000201412,0.01805784],"study_design_scores_gemma":[0.0003351438,0.01001794,0.8975636,0.00004209247,0.000350829,0.0004047557,0.0008016067,0.0006921141,0.08815587,0.0002194253,0.001396358,0.00002028169],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983405,0.001148519,0.0001110762,0.00003838117,0.00001020844,0.000007876705,0.0001058102,0.000001509336,0.0002361018],"genre_scores_gemma":[0.9982395,0.0003115269,0.000111018,0.00003348776,0.00001428315,0.00002658403,0.0001916125,0.000002347527,0.001069707],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001559234,"threshold_uncertainty_score":0.005216122,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01079422704926457,"score_gpt":0.2779334807032064,"score_spread":0.2671392536539419,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}