{"id":"W2987243705","doi":"10.4049/jimmunol.1900872","title":"A TCR β-Chain Motif Biases toward Recognition of Human CD1 Proteins","year":2019,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Australian Research Council; Medical Research Council; National Institutes of Health; National Institute of Allergy and Infectious Diseases; National Health and Medical Research Council","keywords":"T-cell receptor; CD1; Biology; CD1D; Sequence motif; Major histocompatibility complex; Cell biology; Antigen; Gene; Genetics; T cell; CD8; Immune system; Natural killer T cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000107009,0.0001680798,0.0001029294,0.0001765605,0.0001334106,0.0002658693,0.00009224547,0.0001678241,0.003004383],"category_scores_gemma":[0.0002017944,0.00009934173,0.00009106036,0.0001160682,0.0001172597,0.00008061755,0.0001365832,0.0002003253,0.0006792102],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001576511,"about_ca_system_score_gemma":0.0001174875,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003778504,"about_ca_topic_score_gemma":0.0004472203,"domain_scores_codex":[0.9998595,0.00002373533,0.000007220555,0.00004933517,0.00002632941,0.00003384953],"domain_scores_gemma":[0.9999099,0.00002616602,0.00001821954,0.000008873188,0.00001534102,0.00002140967],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001016957,0.000007877241,0.002300508,0.00001927482,0.000005300992,0.00005947804,0.00001654597,0.00004035577,0.9951887,0.00007454029,0.00005675444,0.002129001],"study_design_scores_gemma":[0.00004727101,0.0004369367,0.08036966,0.00003936918,0.00008176948,0.004848606,0.0001542119,0.002817056,0.9005271,0.0003288049,0.0103354,0.00001381572],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961854,0.0004712463,0.001187881,0.0000288739,0.00001086596,0.00001034041,0.0001183821,0.00003384411,0.001953315],"genre_scores_gemma":[0.9981837,0.0001380643,0.0006543916,0.00004477323,0.000004284599,0.000005339537,0.0002302748,0.000008235445,0.0007308983],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003004383,"threshold_uncertainty_score":0.01005065,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03265905720880784,"score_gpt":0.2544186615598324,"score_spread":0.2217596043510246,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}