{"id":"W2987417643","doi":"10.1101/832675","title":"Blocks in tricarboxylic acid cycle of <i>Salmonella enterica</i> cause global perturbation of carbon storage, motility and host-pathogen-interaction","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Regina","funders":"Deutsche Forschungsgemeinschaft","keywords":"Fumarase; Citric acid cycle; Salmonella enterica; Pentose phosphate pathway; Biology; Biochemistry; Glycolysis; Glycogen; Tricarboxylic acid; Fumarate reductase; Metabolic pathway; Metabolism; Microbiology; Cell biology; Mitochondrion; Succinate dehydrogenase; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001061957,0.0004791543,0.0002631909,0.0001535592,0.0001129881,0.0002289038,0.0002804694,0.0002824318,0.001149392],"category_scores_gemma":[0.0001228599,0.0001577263,0.0003113116,0.0001518053,0.000267813,0.0001099399,0.0002516214,0.000399905,0.0002867598],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003697054,"about_ca_system_score_gemma":0.0002346968,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001593641,"about_ca_topic_score_gemma":0.001628832,"domain_scores_codex":[0.9997904,0.0000426827,0.00002766522,0.00004658617,0.00003624116,0.00005649989],"domain_scores_gemma":[0.9997882,0.00002114275,0.00008620149,0.00002724415,0.00001939072,0.00005781696],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002542993,0.00003191738,0.0001894639,0.00002996816,0.000007669643,0.00003684316,0.000006555841,0.00004526698,0.9990228,0.00003638275,0.00002951658,0.0003092723],"study_design_scores_gemma":[0.0000226447,0.0008226433,0.008263729,0.00001053767,0.00002808273,0.000219687,0.00005500776,0.0008653679,0.9884388,0.00004752691,0.001217042,0.00000901433],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971118,0.0003640561,0.001022685,0.0001018196,0.00003409907,0.00002364926,0.0006312396,0.00009258292,0.0006180624],"genre_scores_gemma":[0.9973009,0.0001825957,0.0009383183,0.00007157488,0.000004719987,0.00002761905,0.0006538553,0.00003508204,0.0007853816],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001593641,"threshold_uncertainty_score":0.003845096,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007739765304544426,"score_gpt":0.2164280733487927,"score_spread":0.2086883080442482,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}