{"id":"W2987449891","doi":"10.7554/elife.32579.018","title":"Author response: Transmission genetics of drug-resistant hepatitis C virus","year":2018,"lang":"en","type":"peer-review","venue":"","topic":"Hepatitis C virus research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"NS5A; Hepatitis C virus; NS5B; Biology; Virology; Genome; Phosphoprotein; Computational biology; Virus; Genetics; Drug resistance; NS3; RNA-dependent RNA polymerase; Polymerase; Hepacivirus; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001154471,0.0007875324,0.0005307493,0.0007104103,0.001204698,0.001443386,0.001218796,0.002434487,0.3297079],"category_scores_gemma":[0.004093927,0.0006043309,0.0005507321,0.0007236631,0.000502235,0.001084522,0.001605623,0.001759335,0.1369247],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001275313,"about_ca_system_score_gemma":0.001169291,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002259744,"about_ca_topic_score_gemma":0.003450017,"domain_scores_codex":[0.9990765,0.0001578028,0.00004622954,0.0001602757,0.0004048895,0.0001542507],"domain_scores_gemma":[0.9985972,0.0004235578,0.00007308902,0.0001506619,0.0004895334,0.0002659773],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001029258,0.00002245851,0.0004217584,0.0001962243,0.00001027074,0.0002153156,0.00006023468,0.0002608774,0.003110752,0.003982462,0.9693213,0.02229557],"study_design_scores_gemma":[0.00009164149,0.00003089052,0.001060824,0.0001449846,0.000008528003,0.0003738433,0.0002373262,0.0006196987,0.005846919,0.003619567,0.9879352,0.00003061671],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"commentary","genre_scores_codex":[0.0212937,0.005631336,0.04995742,0.1487259,0.1192025,0.001355617,0.08903889,0.01350997,0.5512846],"genre_scores_gemma":[0.07414952,0.006245581,0.03442236,0.02216292,0.006318938,0.001138606,0.05459088,0.003410985,0.7975601],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.3297079,"threshold_uncertainty_score":0.9560903,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07219077356037877,"score_gpt":0.4065166761555187,"score_spread":0.3343259025951399,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}