{"id":"W2987490438","doi":"10.1111/gtc.12736","title":"Characterization of genetic‐origin‐dependent monoallelic expression in mouse embryonic stem cells","year":2019,"lang":"en","type":"article","venue":"Genes to Cells","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Japan Society for the Promotion of Science; Takeda Medical Research Foundation","keywords":"Biology; Epigenetics; Embryonic stem cell; Genetics; Genomic imprinting; Retrotransposon; Gene; Allele; Induced pluripotent stem cell; X-inactivation; DNA methylation; Gene expression; X chromosome; Transposable element; Genome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001617374,0.0001630768,0.0001731854,0.0005766933,0.0001143182,0.0002617085,0.0001908878,0.0001965541,0.0006690951],"category_scores_gemma":[0.0001527056,0.0001728697,0.0001876299,0.0002849879,0.000127331,0.0001263385,0.0002773471,0.0002836358,0.0003777751],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001176917,"about_ca_system_score_gemma":0.0001207677,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004079138,"about_ca_topic_score_gemma":0.0009139595,"domain_scores_codex":[0.9998424,0.00001435119,0.00002298885,0.00003986926,0.00005447008,0.00002586316],"domain_scores_gemma":[0.9997868,0.00003855797,0.0000620488,0.00003985092,0.00003147436,0.00004130599],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001904862,0.000003838717,0.00138386,0.00001279325,0.000002895963,0.00003457324,0.00001409241,0.00001653278,0.9976708,0.00003426145,0.000003935676,0.0008034016],"study_design_scores_gemma":[0.000005913394,0.0001915197,0.1085838,0.00001007791,0.00003692549,0.0009711622,0.00006545583,0.0008575528,0.8866265,0.00008646467,0.002555562,0.000008938116],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900594,0.001288072,0.006745513,0.00001771283,0.000004441552,0.00003780457,0.0008461317,0.0000593859,0.0009414962],"genre_scores_gemma":[0.991601,0.0006813064,0.003809975,0.00004136817,0.000005036864,0.00006437043,0.001908935,0.00003588211,0.001852096],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006690951,"threshold_uncertainty_score":0.002238333,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008496817429384778,"score_gpt":0.216265221183739,"score_spread":0.2077684037543542,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}