{"id":"W2987590359","doi":"10.1016/j.chest.2019.10.043","title":"Results of an Expert Consensus Survey on the Treatment of Pulmonary Arterial Hypertension With Oral Prostacyclin Pathway Agents","year":2019,"lang":"en","type":"review","venue":"CHEST Journal","topic":"Pulmonary Hypertension Research and Treatments","field":"Medicine","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital; McGill University","funders":"Actelion Pharmaceuticals; School of Dental Medicine, University of Pittsburgh; St. Jude Medical; Cardiovascular Medical Research and Education Fund; Bayer Fund; Acceleron; University of Michigan; United Therapeutics Corporation; Meso Scale Diagnostics; GlaxoSmithKline; Novartis; Pfizer; Boehringer Ingelheim; Edwards Lifesciences; Bristol-Myers Squibb; Gilead Sciences; National Institutes of Health; Medtronic","keywords":"Medicine; Treprostinil; Intensive care medicine; Ambrisentan; Prostacyclin; MEDLINE; Endothelin receptor antagonist; Population; Clinical trial; Pulmonary hypertension; Internal medicine; Cardiology; Bosentan; Endothelin receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007034146,0.000579632,0.002543648,0.0002611261,0.0001291318,0.00002793415,0.0002338582,0.0002758015,0.00006095829],"category_scores_gemma":[0.0002540194,0.0002474666,0.0005271528,0.000267674,0.0002426503,0.00004628352,0.00003336982,0.0004545919,0.00003677873],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002144174,"about_ca_system_score_gemma":0.001229166,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001792379,"about_ca_topic_score_gemma":0.00001299599,"domain_scores_codex":[0.9960871,0.0009803416,0.001092591,0.0004859843,0.0009013422,0.000452608],"domain_scores_gemma":[0.9964906,0.0007344253,0.000925678,0.0009359673,0.0004829134,0.0004304003],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01631707,0.01284852,0.0003490143,0.002185744,0.001984767,0.01929125,0.0001048738,8.910366e-7,0.000269551,0.00000107609,0.001875168,0.9447721],"study_design_scores_gemma":[0.01517266,0.0300898,0.01836779,0.02551048,0.001962097,0.01947516,0.0001581842,0.00008331639,0.000623046,0.000007253095,0.8879026,0.0006475755],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1443252,0.8506747,3.998735e-7,0.0002193084,0.0004755413,0.002831692,0.00111163,0.00001682238,0.0003447568],"genre_scores_gemma":[0.01543167,0.9822704,0.000153973,0.00004968556,0.0002727723,0.00003718259,0.000985363,0.00008423106,0.000714729],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9441245,"threshold_uncertainty_score":0.9999977,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2360503095212629,"score_gpt":0.3829880529331033,"score_spread":0.1469377434118404,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}