{"id":"W2987681697","doi":"10.3390/cancers11111723","title":"Progression-Free but No Overall Survival Benefit for Adult Patients with Bevacizumab Therapy for the Treatment of Newly Diagnosed Glioblastoma: A Systematic Review and Meta-Analysis","year":2019,"lang":"en","type":"review","venue":"Cancers","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Sunnybrook Hospital; St. Michael's Hospital","funders":"","keywords":"Bevacizumab; Medicine; Temozolomide; Meta-analysis; Internal medicine; Hazard ratio; Oncology; Progression-free survival; Randomized controlled trial; Glioblastoma; Radiation therapy; Chemotherapy; Surgery; Confidence interval; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001883611,0.0007578807,0.00920479,0.0001724852,0.00009653364,0.00003144757,0.0002467635,0.0001490594,0.00005099071],"category_scores_gemma":[0.0001822762,0.0002972682,0.003614636,0.0003732335,0.0000663762,0.00004081292,0.00002283054,0.00006393349,0.000003169469],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009460626,"about_ca_system_score_gemma":0.0004401717,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001906479,"about_ca_topic_score_gemma":0.000182344,"domain_scores_codex":[0.9974144,0.00009840717,0.0009903847,0.0006597154,0.0005030327,0.0003340256],"domain_scores_gemma":[0.9946247,0.001580022,0.001323217,0.001411429,0.0009186343,0.0001420177],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.0004069739,0.000558237,0.00004735346,0.6090152,0.3608311,0.000005305742,0.00006175154,0.000006763535,1.425658e-8,0.0000337461,0.0005002646,0.02853331],"study_design_scores_gemma":[0.008552189,0.00579121,0.00001720568,0.03953262,0.9134521,0.00000295027,0.00001354658,0.00001545528,0.000001698308,0.000003117863,0.03233147,0.0002863896],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001235169,0.9622947,0.00001139257,0.0001649163,0.00008840862,0.03471982,0.002572186,0.00001639395,0.000008640562],"genre_scores_gemma":[0.00006660031,0.9607771,0.0002902707,0.0002051771,0.00004267355,0.03789494,0.0004226082,0.00008356092,0.0002170535],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.5694826,"threshold_uncertainty_score":0.999948,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05231020305544352,"score_gpt":0.3398647239761122,"score_spread":0.2875545209206687,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}