{"id":"W2987721755","doi":"10.1021/acsomega.9b02322","title":"Nitrone-Modified Gold Nanoparticles: Synthesis, Characterization, and Their Potential as <sup>18</sup> F-Labeled Positron Emission Tomography Probes via I-SPANC","year":2019,"lang":"en","type":"article","venue":"ACS Omega","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Western University; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Bioorthogonal chemistry; Nitrone; Nanoparticle; Alkyne; Colloidal gold; Chemistry; Cycloaddition; Combinatorial chemistry; Materials science; Nuclear chemistry; Nanotechnology; Click chemistry; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001558317,0.0002787704,0.0002788816,0.000102448,0.0001131841,0.00006530948,0.0001764734,0.0002327195,0.000002289291],"category_scores_gemma":[0.00004244369,0.0002170861,0.0001128394,0.0002035637,0.0000978,0.00002118724,0.0001309957,0.0001053146,0.000006976591],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001276615,"about_ca_system_score_gemma":0.00002699881,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001204822,"about_ca_topic_score_gemma":0.000001635502,"domain_scores_codex":[0.9986179,0.00008952746,0.0002740475,0.0005446725,0.000143104,0.0003307365],"domain_scores_gemma":[0.999162,0.00001691155,0.0001410724,0.0004441479,0.0001243417,0.0001115394],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001603366,0.00009732177,0.001817678,0.00002443708,0.00009869332,0.000001761285,0.00003509763,0.000007141241,0.9920834,0.00000875189,0.0001730091,0.005492401],"study_design_scores_gemma":[0.0003296594,0.0002621669,0.0009484364,0.00004916628,0.0000592253,0.00002211456,0.00005865756,0.0005617699,0.9946989,0.0001021548,0.002601768,0.0003059891],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975435,0.0003168966,0.001333428,0.0002297124,0.00003426684,0.00032673,0.00002714253,0.00008590997,0.0001024307],"genre_scores_gemma":[0.9977262,0.000362493,0.0005439711,0.0002440879,0.0001229505,0.0000265963,0.0002070831,0.00003556,0.0007310486],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005186412,"threshold_uncertainty_score":0.8852516,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004777996454437474,"score_gpt":0.2219049837322927,"score_spread":0.2171269872778552,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}