{"id":"W2987779706","doi":"10.1016/j.neuroscience.2019.10.028","title":"Palmitate and Nitric Oxide Regulate the Expression of Spexin and Galanin Receptors 2 and 3 in Hypothalamic Neurons","year":2019,"lang":"en","type":"article","venue":"Neuroscience","topic":"Apelin-related biomedical research","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Banting and Best Diabetes Centre, University of Toronto; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Health Research; Canada Research Chairs; Canada Foundation for Innovation; Dutch Dairymen Board; Endocrine Society","keywords":"Galanin; Internal medicine; Endocrinology; Receptor; Biology; Nitric oxide; Agonist; Hypothalamus; Signal transduction; G protein-coupled receptor; Neuropeptide; Energy homeostasis; Sodium nitroprusside; Chemistry; Cell biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001309567,0.0002352697,0.0003316209,0.0002798185,0.0003368247,0.000407773,0.0002031442,0.0003488679,0.001096271],"category_scores_gemma":[0.0002193785,0.0002285546,0.0004410069,0.0001430364,0.0004348993,0.0005828072,0.0004808655,0.0006018408,0.0001905007],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000620305,"about_ca_system_score_gemma":0.0002490387,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009791068,"about_ca_topic_score_gemma":0.002090714,"domain_scores_codex":[0.9998467,0.000022536,0.00001068138,0.00003718402,0.00002155529,0.00006122405],"domain_scores_gemma":[0.9998746,0.00002049605,0.00002886506,0.00001350239,0.00001952441,0.00004296569],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001197213,0.00001945934,0.0007620002,0.00002680514,0.00001335099,0.00008870564,0.00004266254,0.00003788201,0.9966029,0.0002027624,0.00003387169,0.0009725133],"study_design_scores_gemma":[0.0001758928,0.0004114518,0.1481947,0.00002930099,0.00008749043,0.000546712,0.0007237299,0.002211862,0.8437466,0.001574536,0.002258817,0.00003879699],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965223,0.001102839,0.001047259,0.0001205268,0.00003805491,0.00000624892,0.0001090867,0.00001397958,0.00103983],"genre_scores_gemma":[0.9947315,0.0006579298,0.0009674286,0.0001374224,0.00002409956,0.0000297516,0.0002098849,0.0000166106,0.003225357],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001096271,"threshold_uncertainty_score":0.004500628,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01963511783748994,"score_gpt":0.279935047555143,"score_spread":0.260299929717653,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}