{"id":"W2987812087","doi":"10.1016/j.mayocp.2019.09.006","title":"Axicabtagene Ciloleucel Chimeric Antigen Receptor T Cell Therapy in Lymphoma With Secondary Central Nervous System Involvement","year":2019,"lang":"en","type":"letter","venue":"Mayo Clinic Proceedings","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba; CancerCare Manitoba","funders":"","keywords":"Medicine; Chimeric antigen receptor; Central nervous system; Lymphoma; Antigen; Immunology; Immunotherapy; Virology; Internal medicine; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004346568,0.0004477177,0.0006855864,0.0005563717,0.001646974,0.001355265,0.0007388389,0.01073096,0.004469928],"category_scores_gemma":[0.001676509,0.0003105208,0.0006657065,0.0004200107,0.0009794561,0.0008014223,0.0004749281,0.006300993,0.00178685],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003147963,"about_ca_system_score_gemma":0.001316876,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003217097,"about_ca_topic_score_gemma":0.00975288,"domain_scores_codex":[0.9996204,0.00008793588,0.00003814113,0.00004275357,0.00007410702,0.0001365624],"domain_scores_gemma":[0.9994637,0.000216788,0.00005896239,0.00002174662,0.00005513806,0.0001836395],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"case_report","study_design_scores_codex":[0.0009652004,0.0003857423,0.0116895,0.0002736663,0.0001102972,0.4364084,0.0001896795,0.0007140726,0.003709688,0.006229167,0.4876842,0.05164042],"study_design_scores_gemma":[0.001364415,0.0009789403,0.01887425,0.0004799377,0.0002422962,0.4570292,0.0003520957,0.005725571,0.004279128,0.01130673,0.4992932,0.00007421453],"study_design_candidate":"case_report","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.05721914,0.01607922,0.001074875,0.8247964,0.01641537,0.000122796,0.0003146258,0.0002454418,0.08373223],"genre_scores_gemma":[0.5701613,0.01244884,0.002012941,0.3074628,0.04996195,0.0001569847,0.0003836336,0.0001018836,0.05730962],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01073096,"threshold_uncertainty_score":0.02284014,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03046165488987711,"score_gpt":0.2736991897576385,"score_spread":0.2432375348677613,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}