{"id":"W2987931165","doi":"10.1016/j.jalz.2017.07.161","title":"[O2–04–01]: CLEARANCE OF BETA‐AMYLOID IS FACILITATED BY APOLIPOPROTEIN E AND CIRCULATING HIGH‐DENSITY LIPOPROTEINS IN BIOENGINEERED HUMAN VESSELS","year":2017,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Cerebral amyloid angiopathy; Pathology; Apolipoprotein E; Context (archaeology); Lumen (anatomy); Amyloid beta; Amyloid (mycology); Medicine; Cognitive decline; Human brain; Cerebral circulation; Dyslipidemia; Dementia; Internal medicine; Biology; Neuroscience; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001662947,0.0001525062,0.0001217393,0.0001013835,0.0001019208,0.0001979072,0.000223817,0.0002983544,0.002354034],"category_scores_gemma":[0.0001043578,0.00006954776,0.0001498866,0.00009338784,0.00009428227,0.0001224195,0.0001117645,0.0002649836,0.0007171521],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009380635,"about_ca_system_score_gemma":0.0001723275,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009504678,"about_ca_topic_score_gemma":0.0007608011,"domain_scores_codex":[0.9999171,0.00001533766,0.000007492579,0.0000191424,0.00002126537,0.00001962454],"domain_scores_gemma":[0.999947,0.00000600249,0.00001053992,0.000006714916,0.00001160885,0.00001827106],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003251326,0.00008192863,0.0001791771,0.00002822284,0.000004498145,0.000188473,0.00002140786,0.00007807343,0.9953401,0.0001937987,0.000218105,0.003341028],"study_design_scores_gemma":[0.00009901253,0.001298762,0.004459637,0.00001463946,0.00002181334,0.0006415565,0.00002818465,0.001937116,0.97442,0.0001327202,0.01693792,0.000008776362],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9823614,0.001044233,0.007413654,0.0002231916,0.0002198393,0.00007350447,0.0003645154,0.0001284191,0.008171243],"genre_scores_gemma":[0.9740457,0.0007853552,0.007437416,0.0002556936,0.00005816225,0.00006691319,0.0009328075,0.00005423044,0.01636379],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002354034,"threshold_uncertainty_score":0.007875025,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03344245749844879,"score_gpt":0.3061564302297222,"score_spread":0.2727139727312734,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}