{"id":"W2987956026","doi":"10.1155/2019/3124745","title":"The Ubiquitin-Specific Protease 18 Promotes Hepatitis C Virus Production by Increasing Viral Infectivity","year":2019,"lang":"en","type":"article","venue":"Mediators of Inflammation","topic":"Hepatitis C virus research","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University; Toronto General Hospital; University of Toronto","funders":"Chinese Academy of Medical Sciences Initiative for Innovative Medicine; National Key Research and Development Program of China; Canadian Institutes of Health Research; Chinese Academy of Medical Sciences; China Scholarship Council; University of Toronto; Dalhousie University; Ministry of Science and Technology of the People's Republic of China","keywords":"Infectivity; Downregulation and upregulation; Replicon; Biology; Virology; Hepatitis C virus; Interferon; CD81; Virus; Viral replication; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00185887,0.0001825873,0.0003007328,0.0001738213,0.0001763299,0.00005670058,0.0001298165,0.0001322739,0.0001787702],"category_scores_gemma":[0.002730129,0.0001400906,0.00008515482,0.0003445309,0.0001819444,0.0004562291,0.00006912898,0.0003503431,0.0002119087],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002540521,"about_ca_system_score_gemma":0.0002104121,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001177103,"about_ca_topic_score_gemma":0.0002235036,"domain_scores_codex":[0.9974823,0.0003978248,0.0005390339,0.000323368,0.0009114663,0.0003459887],"domain_scores_gemma":[0.9983259,0.0002861458,0.0003110768,0.0005113084,0.0004255135,0.0001400914],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002914739,0.00008804374,0.4402596,0.0002146629,0.00003641899,0.000003605626,0.0003601589,0.000003303679,0.4732985,0.0001277186,0.001343232,0.08397321],"study_design_scores_gemma":[0.0008670018,0.0004000254,0.1269315,0.0002166228,0.00002191419,0.00001105854,0.00003954969,0.0005239731,0.8543141,0.0002184624,0.01627861,0.0001771316],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943894,0.0002367604,0.0000738075,0.0008601958,0.0003650249,0.002612484,0.00001806492,0.00009405113,0.001350263],"genre_scores_gemma":[0.9980384,0.0007387649,0.0002310959,0.00001428193,0.0004490067,0.0001977374,0.00008812726,0.00003550219,0.0002071071],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3810156,"threshold_uncertainty_score":0.571273,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01206809959203648,"score_gpt":0.2692734953212464,"score_spread":0.2572053957292099,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}