{"id":"W2987956026","doi":"10.1155/2019/3124745","title":"The Ubiquitin-Specific Protease 18 Promotes Hepatitis C Virus Production by Increasing Viral Infectivity","year":2019,"lang":"en","type":"article","venue":"Mediators of Inflammation","topic":"Hepatitis C virus research","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University; Toronto General Hospital; University of Toronto","funders":"Chinese Academy of Medical Sciences Initiative for Innovative Medicine; National Key Research and Development Program of China; Canadian Institutes of Health Research; Chinese Academy of Medical Sciences; China Scholarship Council; University of Toronto; Dalhousie University; Ministry of Science and Technology of the People's Republic of China","keywords":"Infectivity; Downregulation and upregulation; Replicon; Biology; Virology; Hepatitis C virus; Interferon; CD81; Virus; Viral replication; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001495949,0.0002583525,0.0001996176,0.0001539263,0.0001185315,0.0002660372,0.00008627221,0.0001687903,0.001352741],"category_scores_gemma":[0.0001320925,0.0001033378,0.0002818569,0.0001026726,0.0001978259,0.000143613,0.0001527114,0.0002328155,0.0002772678],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002038351,"about_ca_system_score_gemma":0.0001192815,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001321446,"about_ca_topic_score_gemma":0.0001385863,"domain_scores_codex":[0.9998977,0.00001691984,0.00001144854,0.00002314239,0.00002809854,0.00002263319],"domain_scores_gemma":[0.9998529,0.00002492821,0.00005761197,0.00001470954,0.00001901531,0.00003078252],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001806513,0.00001929233,0.0007903653,0.00004895325,0.0000048764,0.00007230421,0.000008296721,0.00003823705,0.9971542,0.00006295933,0.00004009189,0.001579675],"study_design_scores_gemma":[0.00001746363,0.0004251337,0.01016342,0.000009236553,0.00002233738,0.0004734266,0.00001934113,0.0004802976,0.9860983,0.00006143563,0.002224809,0.000004683845],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958253,0.001749801,0.001267647,0.00007574812,0.00002591604,0.00001639259,0.0002302815,0.00005028417,0.0007587146],"genre_scores_gemma":[0.9969833,0.0008478658,0.001311083,0.0000255475,0.00001428065,0.00001117955,0.0001515503,0.00000794738,0.0006471878],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001352741,"threshold_uncertainty_score":0.004525304,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01206809959203648,"score_gpt":0.2692734953212464,"score_spread":0.2572053957292099,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}