{"id":"W2988013001","doi":"10.1182/blood-2019-130602","title":"Fas Mutations in Non-Hodgkin's Lymphoma (NHL): Implications for Disease Progression and Therapeutic Resistance","year":2019,"lang":"en","type":"article","venue":"Blood","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Lymphoma; Fas receptor; Cancer research; Fas ligand; Immunology; Biology; Immune system; Aggressive lymphoma; Diffuse large B-cell lymphoma; Programmed cell death; Apoptosis; Medicine; Rituximab; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001955311,0.0001305301,0.0001326017,0.0004518179,0.00007143727,0.0002440403,0.0001505151,0.0002648472,0.0008864437],"category_scores_gemma":[0.0002111982,0.00006493113,0.00008066208,0.0001631019,0.0001636757,0.0001752713,0.0001430222,0.0002080707,0.0001211708],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002338716,"about_ca_system_score_gemma":0.0001062932,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001844858,"about_ca_topic_score_gemma":0.0002135332,"domain_scores_codex":[0.9999236,0.00001979368,0.0000101762,0.00001683825,0.00001881806,0.00001086626],"domain_scores_gemma":[0.9998971,0.00002569182,0.00004229149,0.000005242803,0.000008500768,0.00002112187],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001496695,0.0003808534,0.08770528,0.0003909834,0.00005466508,0.004586111,0.0002183871,0.0008899463,0.8314963,0.001888888,0.0004242501,0.07046764],"study_design_scores_gemma":[0.0005112075,0.005526717,0.4186302,0.0002182998,0.0004160128,0.07315782,0.0006442332,0.005921052,0.4646256,0.004254005,0.02604739,0.00004750354],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930303,0.005231013,0.0006093137,0.0001163579,0.00000860977,0.00002452008,0.00009522993,0.00002858675,0.0008561675],"genre_scores_gemma":[0.9971676,0.001782642,0.000428713,0.00004183633,0.00001182222,0.00001077585,0.00009623361,0.000003027707,0.000457373],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008864437,"threshold_uncertainty_score":0.00296545,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006630428746452567,"score_gpt":0.2618584750035237,"score_spread":0.2552280462570711,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}