{"id":"W2988092675","doi":"10.1242/dmm.040998","title":"Formula Feeding and Immature Gut Microcirculation Promote Intestinal Hypoxia leading to Necrotizing Enterocolitis","year":2019,"lang":"en","type":"article","venue":"Disease Models & Mechanisms","topic":"Infant Nutrition and Health","field":"Nursing","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Heart and Stroke Foundation; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"Necrotizing enterocolitis; Hypoxia (environmental); Nitric oxide; Arginine; Blood flow; Biology; Internal medicine; Formula feeding; Microcirculation; Endocrinology; Small intestine; Medicine; Pathology; Chemistry; Biochemistry; Oxygen; Amino acid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001854256,0.0002419692,0.0002712547,0.0002170406,0.0002918696,0.0001748303,0.000104035,0.00009827349,0.00005365636],"category_scores_gemma":[0.00003038824,0.0002638014,0.00009563187,0.0001604608,0.00001223043,0.0005164302,0.00007631185,0.0002162214,0.0001124367],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001832541,"about_ca_system_score_gemma":0.0000324559,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003206924,"about_ca_topic_score_gemma":0.000006059117,"domain_scores_codex":[0.9983354,0.00004598699,0.000313022,0.0004836637,0.000294282,0.0005275989],"domain_scores_gemma":[0.9990546,0.00002835524,0.0001086236,0.0002164661,0.00012072,0.0004712887],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.001492391,0.0001440899,0.0004168057,0.001113033,0.00002371741,0.00003780991,0.004579529,0.000878175,0.9221306,0.06300447,0.0005425051,0.005636869],"study_design_scores_gemma":[0.005630283,0.0007539846,0.01284789,0.005042295,0.0002843203,0.0002843727,0.001548035,0.5564222,0.04410768,0.3688453,0.002163495,0.002070168],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9205779,0.0001425084,0.0746021,0.001824666,0.0005198519,0.001637007,0.0000502584,0.0002095501,0.0004361697],"genre_scores_gemma":[0.9854902,0.000005220748,0.01166254,0.002346742,0.0001283702,0.0000692808,0.00007459468,0.00005468662,0.0001683674],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8780229,"threshold_uncertainty_score":0.9999814,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01630560900278123,"score_gpt":0.2654052614724465,"score_spread":0.2490996524696653,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}