{"id":"W2988465249","doi":"10.1182/blood-2019-127185","title":"Clinical Utility of Telomere Length-Directed Genomic Assessment in Patients with Short Telomere Syndromes","year":2019,"lang":"en","type":"article","venue":"Blood","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Telomere; Medicine; Genetic testing; Telomerase; Internal medicine; Biology; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005125211,0.0004270625,0.0002453529,0.001172724,0.0002558203,0.0004650823,0.0003136395,0.0004234328,0.001750564],"category_scores_gemma":[0.001781257,0.00007770754,0.0001502386,0.0004431673,0.0002725903,0.0003274269,0.0003025768,0.0003438611,0.0003671764],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002331519,"about_ca_system_score_gemma":0.000273194,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001594976,"about_ca_topic_score_gemma":0.002132142,"domain_scores_codex":[0.9998052,0.00005240615,0.00002686241,0.00005031758,0.00003807106,0.00002726806],"domain_scores_gemma":[0.9993548,0.0002126898,0.000138545,0.00002280674,0.0001122534,0.000158964],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000325043,0.00002741806,0.9838471,0.00002773438,0.00001065278,0.002299255,0.00009600557,0.0001718973,0.001634422,0.00007198087,0.0005055984,0.01098284],"study_design_scores_gemma":[0.0000388264,0.0006475222,0.975958,0.0000922613,0.00005922973,0.01715917,0.0003806408,0.00183164,0.001655535,0.0003392302,0.001819651,0.00001820524],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920421,0.001259561,0.000555585,0.0003535663,0.00002784675,0.00004404225,0.0005076184,0.00004256664,0.005167124],"genre_scores_gemma":[0.9983138,0.0002657725,0.0007077628,0.00008361499,0.00002701488,0.00001304836,0.0003276492,0.000003281574,0.0002580972],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001750564,"threshold_uncertainty_score":0.005856216,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01938371925959553,"score_gpt":0.2956137867808679,"score_spread":0.2762300675212724,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}