{"id":"W2988583371","doi":"10.1371/journal.pone.0225186","title":"Mineral absorption is an enriched pathway in a brain region of restless legs syndrome patients with reduced MEIS1 expression","year":2019,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Restless Legs Syndrome Research","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Douglas Mental Health University Institute; McGill University; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research","keywords":"Gene; Biology; Gene expression; Biological pathway; Intracellular; Regulation of gene expression; RNA; Cell biology; Oxidative stress; Genetics; Internal medicine; Endocrinology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007203007,0.0003036336,0.0003442706,0.0005127552,0.0002377928,0.0002753364,0.0001360191,0.0002606376,0.001845734],"category_scores_gemma":[0.0001983485,0.0001197484,0.0004515951,0.0003577351,0.000200872,0.0001127523,0.0002203398,0.0003258736,0.0002963307],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001763914,"about_ca_system_score_gemma":0.0001824014,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002522098,"about_ca_topic_score_gemma":0.003877105,"domain_scores_codex":[0.9999079,0.000005266232,0.000005851483,0.00004805366,0.0000189112,0.00001403291],"domain_scores_gemma":[0.9998922,0.00002531438,0.0000443553,0.000006348476,0.00001537959,0.00001632184],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001822133,0.00004697457,0.1687407,0.0004594294,0.0005328186,0.003870143,0.0004247593,0.0007887279,0.8009857,0.0002101892,0.002047298,0.02007106],"study_design_scores_gemma":[0.00005485254,0.0001482347,0.9399449,0.00005043806,0.0003839829,0.005494075,0.0003408656,0.001767638,0.04623839,0.0006379889,0.004909436,0.00002922223],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901056,0.002009924,0.001543325,0.0001713724,0.00001970956,0.00001069541,0.005356994,0.0001248467,0.0006575398],"genre_scores_gemma":[0.9899262,0.0007350835,0.002090723,0.0002238202,0.00001840951,0.00003124595,0.005196714,0.00005432081,0.001723427],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002522098,"threshold_uncertainty_score":0.006174624,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05823692074479887,"score_gpt":0.2741925407774373,"score_spread":0.2159556200326385,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}