{"id":"W2988772870","doi":"10.1038/s41598-019-52964-2","title":"Structures of GapR reveal a central channel which could accommodate B-DNA","year":2019,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; University of Ottawa; McGill University","funders":"National Research Council Canada; Western Economic Diversification Canada; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Canada Research Chairs; Government of Canada; University of Saskatchewan; Canadian Light Source","keywords":"Tetramer; DNA; Nucleoid; Biophysics; Helix (gastropod); Binding site; Biology; DNA-binding protein; Crystallography; Chemistry; Cell biology; Genetics; Biochemistry; Escherichia coli; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002091475,0.0002525679,0.0004692262,0.0001695512,0.0002775381,0.0005855414,0.0003686172,0.0009336594,0.001072169],"category_scores_gemma":[0.000372338,0.0002522668,0.0003515601,0.0002096495,0.0003351513,0.0006737323,0.0003571367,0.001176286,0.0004990203],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003976475,"about_ca_system_score_gemma":0.0003147037,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006082,"about_ca_topic_score_gemma":0.0005698367,"domain_scores_codex":[0.9999024,0.00001304426,0.000006807133,0.00003069375,0.00002877003,0.00001842013],"domain_scores_gemma":[0.9997044,0.00006229769,0.00009211314,0.00003261895,0.00002453902,0.00008397042],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005878881,0.0001250247,0.002186012,0.0003203194,0.00004973846,0.001741806,0.0002572514,0.002380874,0.9796267,0.003115363,0.001142181,0.008466916],"study_design_scores_gemma":[0.0004127048,0.0009299123,0.03360786,0.0001137528,0.0001496867,0.008231166,0.0006579235,0.04058249,0.8756126,0.004990086,0.03451572,0.000196157],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.987199,0.001932633,0.006642848,0.0004956809,0.00004146956,0.00001905526,0.0006064377,0.000327723,0.002735206],"genre_scores_gemma":[0.9862728,0.0005565842,0.01081895,0.0001454296,0.00001759884,0.00001505214,0.001187658,0.00004435738,0.0009415581],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001072169,"threshold_uncertainty_score":0.003586769,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007625147396744523,"score_gpt":0.2272755912274832,"score_spread":0.2196504438307387,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}