{"id":"W2988876512","doi":"10.1128/msphere.00660-19","title":"Loss of <i>O</i> -Linked Protein Glycosylation in Burkholderia cenocepacia Impairs Biofilm Formation and Siderophore Activity and Alters Transcriptional Regulators","year":2019,"lang":"en","type":"article","venue":"mSphere","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"National Health and Medical Research Council; Australian Research Council; Medical Research Council; Department of Education and Training; University of Melbourne; UK Research and Innovation","keywords":"Burkholderia cenocepacia; Glycosylation; Biology; Proteome; Glycoprotein; Quorum sensing; Campylobacter jejuni; Biofilm; Phenotype; Cell biology; N-linked glycosylation; Glycan; Microbiology; Gene; Genetics; Virulence; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008504005,0.0001103519,0.0001357645,0.00003104088,0.00002156148,0.00001234847,0.00005085504,0.0002532799,0.00001873157],"category_scores_gemma":[0.000007703892,0.0001057088,0.0000279481,0.00007011911,0.00008301497,0.00001003037,0.00003891962,0.00006717097,9.618873e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009750974,"about_ca_system_score_gemma":0.00002360077,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005267466,"about_ca_topic_score_gemma":0.0001495429,"domain_scores_codex":[0.9993902,0.00003170501,0.0001605099,0.0002193294,0.00006406513,0.0001341742],"domain_scores_gemma":[0.9997117,0.000002860725,0.00008300267,0.0001409682,0.0000292712,0.0000322241],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001828889,0.00002464803,0.006247353,0.00007055686,0.000009933782,4.35276e-7,0.00004297594,0.000009939264,0.9893715,0.0001076111,0.000008617004,0.003923521],"study_design_scores_gemma":[0.0009425905,0.0003681691,0.09010497,0.00003174505,0.000006215569,0.00001129993,0.00006544799,0.0002608071,0.9066662,0.0002049951,0.001194361,0.0001432],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989249,0.0003052767,0.00008488919,0.0001839209,0.00005398697,0.0003505374,0.00002536484,0.000006626967,0.00006452087],"genre_scores_gemma":[0.9992837,0.0001382236,0.0004240096,0.00001932768,0.00002574908,0.000008952792,0.00004658488,0.00001025544,0.00004315833],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08385763,"threshold_uncertainty_score":0.4310679,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005740500998141451,"score_gpt":0.201134850207944,"score_spread":0.1953943492098026,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}