{"id":"W2988876512","doi":"10.1128/msphere.00660-19","title":"Loss of <i>O</i> -Linked Protein Glycosylation in Burkholderia cenocepacia Impairs Biofilm Formation and Siderophore Activity and Alters Transcriptional Regulators","year":2019,"lang":"en","type":"article","venue":"mSphere","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"National Health and Medical Research Council; Australian Research Council; Medical Research Council; Department of Education and Training; University of Melbourne; UK Research and Innovation","keywords":"Burkholderia cenocepacia; Glycosylation; Biology; Proteome; Glycoprotein; Quorum sensing; Campylobacter jejuni; Biofilm; Phenotype; Cell biology; N-linked glycosylation; Glycan; Microbiology; Gene; Genetics; Virulence; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001185795,0.0003098787,0.0001672016,0.000109495,0.00008694464,0.0002524307,0.0001574077,0.0001844708,0.0005199079],"category_scores_gemma":[0.0001247655,0.0001159028,0.0001537966,0.0001184787,0.0002230918,0.0001370003,0.0001975335,0.0003449963,0.0002134109],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002015603,"about_ca_system_score_gemma":0.0001816783,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001049087,"about_ca_topic_score_gemma":0.001117009,"domain_scores_codex":[0.9998485,0.00003522291,0.00001943036,0.00002137666,0.00004030344,0.00003512688],"domain_scores_gemma":[0.9998494,0.00002037312,0.00005876701,0.00002259333,0.00001072457,0.00003811034],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004196433,0.00001592398,0.0001865545,0.000006502102,0.000001784371,0.00001657506,0.000004083138,0.000021319,0.9994156,0.00001829466,0.000006334742,0.0002650622],"study_design_scores_gemma":[0.000005659973,0.0001699472,0.007329378,0.000003175008,0.000005682413,0.0001229494,0.00003758316,0.0004354776,0.9913108,0.00003338065,0.0005428728,0.0000030422],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979901,0.0002415096,0.001193699,0.00006796425,0.000009694085,0.000005811658,0.0001569885,0.00003089439,0.0003033311],"genre_scores_gemma":[0.9978871,0.0001572562,0.001216152,0.00003227951,0.000002189527,0.000008050492,0.0001590562,0.00001401339,0.0005238835],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001049087,"threshold_uncertainty_score":0.002085984,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005740500998141451,"score_gpt":0.201134850207944,"score_spread":0.1953943492098026,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}