{"id":"W2988880770","doi":"10.1002/open.201900273","title":"Hyperpolarization of Pyridyl Fentalogues by Signal Amplification By Reversible Exchange (SABRE)","year":2019,"lang":"en","type":"article","venue":"ChemistryOpen","topic":"Advanced NMR Techniques and Applications","field":"Chemistry","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Manchester Metropolitan University","keywords":"IMes; Chemistry; Hyperpolarization (physics); Hydride; Fentanyl; Heroin; Ligand (biochemistry); Stereochemistry; Carbene; Nuclear magnetic resonance spectroscopy; Pharmacology; Organic chemistry; Metal; Medicine; Receptor; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002444889,0.0002878414,0.0001245378,0.0001095029,0.0001325098,0.0001531381,0.0002424856,0.0002439417,0.001826306],"category_scores_gemma":[0.0002576028,0.0001412704,0.0001110256,0.000085839,0.000312225,0.0002938428,0.0002985194,0.0004507145,0.0003517958],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001180262,"about_ca_system_score_gemma":0.00008504371,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001911291,"about_ca_topic_score_gemma":0.0003005722,"domain_scores_codex":[0.9998643,0.0000356916,0.000004226565,0.00003035631,0.00003042123,0.00003505027],"domain_scores_gemma":[0.9999022,0.00003020936,0.00003222308,0.0000107693,0.00001410733,0.00001052192],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007562292,0.000006289508,0.00003479007,0.00003620049,0.000002691096,0.00003473521,0.00004416332,0.00004864122,0.998276,0.0001387824,0.00004481996,0.001257324],"study_design_scores_gemma":[0.000006952243,0.0001157145,0.0001686191,0.000002605627,0.000002504213,0.00006359214,0.00001591594,0.000377804,0.9984835,0.00002346648,0.0007364401,0.000003028744],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9816466,0.0005398353,0.01353594,0.0001453596,0.00002676413,0.00004160483,0.00005779272,0.0001803893,0.003825706],"genre_scores_gemma":[0.9912748,0.000269141,0.005965459,0.00007665677,0.000008551986,0.00002031524,0.00005425917,0.00003500797,0.002295794],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001826306,"threshold_uncertainty_score":0.006109655,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009443419865022656,"score_gpt":0.2423941848323755,"score_spread":0.2329507649673528,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}