{"id":"W2988888269","doi":"10.1038/s42003-019-0633-x","title":"Spatial structure affects phage efficacy in infecting dual-strain biofilms of Pseudomonas aeruginosa","year":2019,"lang":"en","type":"article","venue":"Communications Biology","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Université de Lausanne; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Lytic cycle; Microbiology; Pseudomonas aeruginosa; Strain (injury); Biology; Bacteria; Biofilm; Bacteriophage; Nutrient agar; Phage therapy; Bacterial virus; Agar; Virology; Escherichia coli; Virus; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001193238,0.0001044784,0.0001734246,0.00006585224,0.00007160713,0.000008952542,0.0004341847,0.0001144332,0.001971174],"category_scores_gemma":[0.00005550897,0.0000981712,0.00005183989,0.000221938,0.0002536195,0.00009002846,0.0005308818,0.0002658671,0.0001896149],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006346698,"about_ca_system_score_gemma":0.00001133178,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001507047,"about_ca_topic_score_gemma":0.002763841,"domain_scores_codex":[0.9991971,0.0001923698,0.0002173204,0.0001816869,0.00003033618,0.000181167],"domain_scores_gemma":[0.9987257,0.0002481369,0.0001348538,0.000852655,0.00000747357,0.00003115719],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000004994824,0.0001243695,0.1019978,0.00000453093,0.000007110774,3.354857e-7,0.0002662103,0.00004741605,0.8901374,0.0002859112,0.00002509268,0.007098821],"study_design_scores_gemma":[0.0007281853,0.0001418513,0.9375478,0.00004151857,0.00001175363,0.00002599993,0.0001185772,0.0003369478,0.05450345,0.000117375,0.006223943,0.0002025809],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949034,0.0000497436,0.00004131754,0.000274132,0.0001601989,0.0002790752,0.0001087194,0.00002104367,0.004162306],"genre_scores_gemma":[0.9980311,0.00004840766,0.001586245,0.00007218828,0.00001308663,0.000007910601,0.0001570963,0.000008447936,0.00007545363],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8356339,"threshold_uncertainty_score":0.9989412,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01259138148340984,"score_gpt":0.2775008019292045,"score_spread":0.2649094204457947,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}