{"id":"W2989003490","doi":"10.1016/j.bbadis.2019.165591","title":"Epidemiology and pathogenesis of maternal-fetal transmission of Trypanosoma cruzi and a case for vaccine development against congenital Chagas disease","year":2019,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","topic":"Trypanosoma species research and implications","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Emory Eye Center; Composites Innovation Centre; National Institute of Allergy and Infectious Diseases; National Institutes of Health; Comisión de Investigaciones Científicas; Consejo Nacional de Investigaciones Científicas y Técnicas","keywords":"Benznidazole; Nifurtimox; Chagas disease; Trypanosoma cruzi; Medicine; Pathogenesis; Transmission (telecommunications); Asymptomatic; Pregnancy; Disease; Fetus; Immunology; Epidemiology; Intensive care medicine; Biology; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007165198,0.0005734994,0.001180043,0.001907002,0.0001987206,0.0008341125,0.0007334565,0.001302675,0.001535048],"category_scores_gemma":[0.001109938,0.0002562648,0.0002932615,0.001954674,0.0006701454,0.001187753,0.0005100773,0.001290379,0.000571392],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000839852,"about_ca_system_score_gemma":0.001755622,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003698902,"about_ca_topic_score_gemma":0.004818038,"domain_scores_codex":[0.9998041,0.00005368791,0.00003989808,0.00002775916,0.00005053402,0.00002402107],"domain_scores_gemma":[0.9994884,0.0002986167,0.00008113647,0.000008900791,0.00009469202,0.00002826072],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001296812,0.00005591991,0.001500634,0.02831514,0.0001539267,0.0007935439,0.0001838528,0.0004882012,0.00104468,0.008129275,0.03504427,0.9241608],"study_design_scores_gemma":[0.00003656075,0.000137887,0.00599385,0.01910975,0.0004590045,0.005841643,0.0004704766,0.0001988865,0.0002937194,0.005661776,0.9617478,0.00004859465],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005472816,0.9995226,0.00002031428,0.0002031795,0.00005005303,7.658664e-7,0.000004887977,7.919905e-7,0.0001427992],"genre_scores_gemma":[0.0005223966,0.9991648,0.00003846741,0.00008967205,0.0001154795,0.000001162654,0.000008213814,2.040161e-7,0.00005947038],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003698902,"threshold_uncertainty_score":0.007354796,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04881444629225823,"score_gpt":0.3495199094218212,"score_spread":0.3007054631295629,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}