{"id":"W2989015144","doi":"10.1016/j.ygcen.2019.113325","title":"Twenty years of transcriptomics, 17alpha-ethinylestradiol, and fish","year":2019,"lang":"en","type":"review","venue":"General and Comparative Endocrinology","topic":"Reproductive biology and impacts on aquatic species","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":false,"ca_institutions":"Wilfrid Laurier University; University of New Brunswick","funders":"National Institute of Environmental Health Sciences; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; National Institutes of Health; National Science Foundation","keywords":"Biology; Vitellogenin; Transcriptome; Toxicogenomics; Estrogen receptor; Zebrafish; Estriol; GPER; Oryzias; Vitellogenins; Estrogen; Danio; Computational biology; Endocrinology; Gene; Genetics; Gene expression; Vitellogenesis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001063399,0.0008577793,0.001541983,0.001768813,0.0003089654,0.00150487,0.0008838397,0.001490108,0.004744916],"category_scores_gemma":[0.001077566,0.0003362112,0.0005054448,0.003271943,0.0009105813,0.001783809,0.001121295,0.001645717,0.001884085],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001022731,"about_ca_system_score_gemma":0.002090454,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002571242,"about_ca_topic_score_gemma":0.004431011,"domain_scores_codex":[0.9997903,0.00002239667,0.00002536948,0.00007336467,0.00006636933,0.00002225852],"domain_scores_gemma":[0.999418,0.0002935962,0.00006390054,0.00002648603,0.0001372528,0.0000608068],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001351422,0.00004794075,0.0004785412,0.008020986,0.00008176692,0.0001188788,0.00005127463,0.0003939214,0.004205528,0.005631567,0.02339673,0.9574378],"study_design_scores_gemma":[0.00001306097,0.00007202787,0.001692749,0.00195653,0.0001232368,0.0003583254,0.000113748,0.00009612434,0.00114489,0.003543759,0.9908606,0.00002483779],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001461909,0.9978638,0.000267552,0.0004958576,0.0003142084,0.000002509363,0.00005568617,0.00000917424,0.0008449321],"genre_scores_gemma":[0.0006709977,0.9972489,0.0002973762,0.0003748701,0.0003256024,0.000005318484,0.00008500912,0.000002673251,0.000989089],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004744916,"threshold_uncertainty_score":0.01587331,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1024016373977206,"score_gpt":0.3410211117397892,"score_spread":0.2386194743420686,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}