{"id":"W2989077172","doi":"10.1182/blood-2019-123426","title":"Daratumumab Plus Lenalidomide and Dexamethasone (D-Rd) Versus Lenalidomide and Dexamethasone (Rd) in Patients with Newly Diagnosed Multiple Myeloma (NDMM) Ineligible for Transplant: Updated Analysis of Maia","year":2019,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research; University of Alberta; University of Calgary","funders":"","keywords":"Medicine; Lenalidomide; Internal medicine; Daratumumab; Hazard ratio; Multiple myeloma; Transplantation; Oncology; Surgery; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003200041,0.0004337388,0.001710825,0.0006250642,0.0001889952,0.00126721,0.0007744451,0.0004749505,0.00182118],"category_scores_gemma":[0.003316034,0.0002659758,0.002816684,0.001036573,0.0002225445,0.0006839259,0.0004915061,0.001549563,0.0002473354],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009997536,"about_ca_system_score_gemma":0.0008931413,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001484121,"about_ca_topic_score_gemma":0.006215107,"domain_scores_codex":[0.9990722,0.0004128125,0.0001013749,0.0001554751,0.0001794009,0.00007881715],"domain_scores_gemma":[0.9969946,0.001056441,0.001222893,0.0001262077,0.0002379407,0.0003619603],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.2352484,0.001424283,0.3073787,0.005198132,0.0266121,0.0003052374,0.0003003098,0.00448708,0.006611066,0.0006954744,0.01482418,0.3969149],"study_design_scores_gemma":[0.06100875,0.04314006,0.7889291,0.001551907,0.05222568,0.001806699,0.0002044736,0.005253696,0.002771697,0.001128703,0.04183201,0.0001472451],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8812404,0.1010133,0.0007241522,0.002294907,0.0002833788,0.0003641773,0.009120319,0.00008242909,0.00487689],"genre_scores_gemma":[0.9698658,0.01532175,0.001175799,0.001946656,0.0004384313,0.000237119,0.009992006,0.00002133124,0.001001123],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003200041,"threshold_uncertainty_score":0.01692361,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01626061945225429,"score_gpt":0.2651019646184587,"score_spread":0.2488413451662044,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}