{"id":"W2989089017","doi":"10.1182/blood-2019-124842","title":"Clingen Coagulation Factor Deficiency Variant Curation Expert Panel: Meeting the Need for Recommendations to Curate Variants in the Coagulation Factor Genes","year":2019,"lang":"en","type":"article","venue":"Blood","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Genetics; Coagulation; Gene; Computational biology; Medical genetics; Bioinformatics; Medicine; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.07513017,0.001091805,0.002801202,0.005123474,0.003116149,0.007295522,0.006221926,0.01691425,0.01474313],"category_scores_gemma":[0.1995288,0.001174907,0.003536822,0.003019824,0.00221849,0.004826704,0.006085463,0.01908109,0.01568455],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004985173,"about_ca_system_score_gemma":0.02947605,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007241045,"about_ca_topic_score_gemma":0.01557108,"domain_scores_codex":[0.9501459,0.02218477,0.01077661,0.002690639,0.01159706,0.002604981],"domain_scores_gemma":[0.746772,0.0588668,0.01197523,0.007338357,0.1577643,0.01728328],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000392848,0.00004328876,0.0008323991,0.0009524963,0.00004775963,0.0002638535,0.0002468768,0.0001355979,0.0003293261,0.001309105,0.9359885,0.05981142],"study_design_scores_gemma":[0.0001755248,0.00003924739,0.001672542,0.007750424,0.00009530366,0.0005977078,0.0003578205,0.0004798454,0.0003060512,0.006282647,0.9821432,0.00009977313],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"methods","genre_scores_codex":[0.001678712,0.01725042,0.02672327,0.8749875,0.02805119,0.005346227,0.00385627,0.001875853,0.04023055],"genre_scores_gemma":[0.01672966,0.02344066,0.26884,0.6137798,0.02391729,0.009956041,0.01164971,0.001174542,0.03051222],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.07513017,"threshold_uncertainty_score":0.3973311,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1138890599669322,"score_gpt":0.3643568991763542,"score_spread":0.250467839209422,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}